Vitamin D deficiency and supplementation in pregnancy in a multiethnic population-based cohort

BMC Pregnancy and Childbirth
Åse R EggemoenAnne K Jenum

Abstract

To investigate ethnic differences in vitamin D levels during pregnancy, assess risk factors for vitamin D deficiency and explore the effect of vitamin D supplementation in women with deficiency in early pregnancy. This is a population-based, multiethnic cohort study of pregnant women attending Child Health Clinics for antenatal care in Oslo, Norway. Serum-25-hydroxyvitamin D [25(OH)D] was measured in 748 pregnant women (59% ethnic minorities) at gestational weeks (GW) 15 (SD:3.6) and 28 (1.4). Women with 25(OH)D <37 nmol/L at GW 15 were for ethical reasons recommended vitamin D3 supplementation. Main outcome measure was 25(OH)D, and linear regression models were performed. Severe deficiency (25(OH)D <25 nmol/L) was found at GW 15 in 45% of women from South Asia, 40% from the Middle East and 26% from Sub-Saharan Africa, compared to 2.5% in women from East Asia and 1.3% of women from Western Europe. Women from South Asia, the Middle East and Sub-Saharan Africa had mean values that were -28 (95 % CI:-33, -23), -24 (-29, -18) and -20 (-27, -13) nmol/L lower than in Western women, respectively. Ethnicity, education, season and intake of vitamin D were independently associated with 25(OH)D. At GW 28, the mean 25(OH)D had increased fr...Continue Reading

References

Oct 1, 1986·The Journal of Clinical Endocrinology and Metabolism·D D BikleJ G Haddad
Jul 1, 1995·European Journal of Obstetrics, Gynecology, and Reproductive Biology·H W Bruinse, H van den Berg
Aug 29, 2002·BJOG : an International Journal of Obstetrics and Gynaecology·S DattaB Richards
Jan 9, 2007·The American Journal of Clinical Nutrition·John N HathcockRobert Heaney
Jul 20, 2007·The New England Journal of Medicine·Michael F Holick
Aug 2, 2007·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Magritt BrustadEiliv Lund
Apr 24, 2008·The British Journal of Nutrition·Lisa M BodnarMark A Klebanoff
Jul 23, 2008·Annals of Nutrition & Metabolism·Margaretha HaugenHelle Margrete Meltzer
Sep 6, 2008·Clinical Endocrinology·C K H YuS Robinson
Oct 23, 2009·American Journal of Obstetrics and Gynecology·Megan L MulliganCarlos Bernal-Mizrachi
May 13, 2010·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·I M van der MeerP Lips
Dec 2, 2010·The Journal of Clinical Endocrinology and Metabolism·A Catharine RossSue A Shapses
Mar 18, 2011·Acta Paediatrica·Maria SääfGunnel Bågenholm
Jun 8, 2011·The Journal of Clinical Endocrinology and Metabolism·Michael F HolickUNKNOWN Endocrine Society
Jun 28, 2011·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Bruce W HollisCarol L Wagner
Nov 22, 2011·Journal of Perinatal Medicine·Nils MilmanThomas Bergholt
Feb 18, 2012·The Cochrane Database of Systematic Reviews·Luz Maria De-RegilJuan Pablo Peña-Rosas
Feb 22, 2012·European Journal of Nutrition·Gerrit van den BergReinoud J B J Gemke
Mar 24, 2012·The Journal of Clinical Endocrinology and Metabolism·Clifford J RosenChristine L Taylor
Jul 7, 2012·Paediatric and Perinatal Epidemiology·Andrew Thorne-Lyman, Wafaie W Fawzi
Dec 6, 2012·Acta Obstetricia Et Gynecologica Scandinavica·Henrik T ChristesenJan S Jørgensen
Dec 12, 2012·European Journal of Nutrition·Nicola PrincipiSusanna Esposito
Sep 17, 2013·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·C ToherF M McAuliffe
Nov 12, 2013·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Ingrid BergströmAgneta Blanck
Jan 24, 2014·European Journal of Endocrinology·Kristin GodangJens Bollerslev
Jul 16, 2014·Health Technology Assessment : HTA·Nicholas C HarveyCyrus Cooper
Aug 28, 2014·The British Journal of Nutrition·Joy Y ZhangMairead Kiely
Sep 12, 2014·BJOG : an International Journal of Obstetrics and Gynaecology·A RodriguezE Morales
Apr 23, 2015·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Miranda Davies-TuckEuan Wallace

❮ Previous
Next ❯

Citations

Apr 20, 2017·Maternal & Child Nutrition·Anthoney J B EmmersonJacqueline L Berry
Feb 13, 2019·International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition·Claudia SavardAnne-Sophie Morisset
Jun 24, 2016·Nature Reviews. Disease Primers·Elizabeth A StewartBeverley Vollenhoven
Jun 9, 2017·Hormone Molecular Biology and Clinical Investigation·Chui Ling LeeNor Azlin Mohamed Ismail
Jan 10, 2020·Scandinavian Journal of Public Health·Suvi T ItkonenChristel J E Lamberg-Allardt
Jun 1, 2018·Journal of Diabetes Research·Åse Ruth EggemoenAnne Karen Jenum
May 9, 2019·The Journal of Medical Investigation : JMI·Eishi SogawaMinoru Irahara
Feb 6, 2017·The Journal of Obstetrics and Gynaecology Research·Shan-Shan ZhouFang-Biao Tao
Feb 13, 2020·The Proceedings of the Nutrition Society·Andrea L Darling
Dec 12, 2019·Frontiers in Immunology·Farhan CyprianGuillermina Girardi
Dec 22, 2019·Journal of the American Academy of Child and Adolescent Psychiatry·Minna SucksdorffAndre Sourander
Nov 24, 2021·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·B SevenH L Keskin

❮ Previous
Next ❯

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.