Vitamin D deficiency in alopecia areata

The British Journal of Dermatology
A Aksu CermanI Kivanc Altunay

Abstract

Alopecia areata (AA) is a T cell-mediated autoimmune disease that causes inflammation around anagen-stage hair follicles. Insufficient levels of vitamin D have been implicated in a variety of autoimmune diseases. Previous reports have described the effects of vitamin D on hair follicles. To evaluate the status of vitamin D in patients with AA, and the relationship between vitamin D levels and disease severity. A cross-sectional study of 86 patients with AA, 44 patients with vitiligo and 58 healthy controls was conducted. The serum vitamin D levels of the study group were determined by liquid chromatography/tandem mass spectrometry. Serum 25-hydroxyvitamin D [25(OH)D] levels in patients with AA were significantly lower than those of the patients with vitiligo and the healthy controls (P = 0·001 and P < 0·001, respectively). The prevalence of 25(OH)D deficiency was significantly higher in patients with AA (91%) compared with patients with vitiligo (71%) and healthy controls (33%) (P = 0·003 and P < 0·001, respectively). Furthermore, a significant inverse correlation was found between disease severity and serum 25(OH)D level in patients with AA (r = -0·409; P < 0·001). Deficient serum 25(OH)D levels are present in patients with AA...Continue Reading

References

Oct 28, 1999·Experimental Dermatology·K J McElweeJ P Sundberg
May 30, 2002·The American Journal of Medicine·Vin TangprichaMichael F Holick
Aug 29, 2003·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Sarah J LewisAndrew C Povey
Dec 13, 2005·Autoimmunity Reviews·Amos Gilhar, Richard S Kalish
Jun 15, 2007·Annals of the Rheumatic Diseases·Yoav ArnsonYehuda Shoenfeld
Feb 2, 2010·Journal of the American Academy of Dermatology·Abdullah AlkhalifahJerry Shapiro
May 15, 2010·Journal of the American Academy of Dermatology·Sibel Ersoy-Evans
Sep 14, 2010·Photodermatology, Photoimmunology & Photomedicine·Matteo C LoPiccolo, Henry W Lim
Jun 15, 2011·Molecular and Cellular Endocrinology·Daniel D Bikle
Jun 22, 2011·Dermatologic Therapy·Elise A Olsen
Jun 22, 2011·Dermatologic Therapy·Eddy Wang, Kevin J McElwee
Jun 23, 2011·Molecular and Cellular Endocrinology·Peter J Malloy, David Feldman
Sep 8, 2011·Immunology·Michelino Di RosaLucia Malaguarnera
Oct 15, 2011·Clinical Endocrinology·Martin Hewison
Oct 22, 2011·The British Journal of Dermatology·P GisondiG Girolomoni
Aug 11, 2012·Annals of Dermatology·Dong Ha KimMyeung Nam Kim
Sep 18, 2012·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Deborah M MitchellSherri-Ann M Burnett-Bowie
Jan 4, 2013·Photodermatology, Photoimmunology & Photomedicine·Hanan M A SalehHeba-Tullah M M Hamza
Jan 17, 2013·Therapeutic Advances in Endocrinology and Metabolism·Ifigenia Kostoglou-AthanassiouChristodoulos Antoniadis
Mar 23, 2013·Nutrients·Simon Vanlint
Aug 21, 2013·Experimental Dermatology·K J McElweeR Paus
Oct 15, 2013·International Journal of Rheumatic Diseases·Alireza KhabbaziSousan Kolahi
Nov 7, 2013·Dermato-endocrinology·Roberto d'OvidioFrancesco Domenico d'Ovidio

❮ Previous
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Citations

Nov 10, 2015·Expert Review of Clinical Immunology·Hongwei GuoKevin McElwee
Oct 22, 2014·Expert Opinion on Emerging Drugs·Leyre Falto-AizpuruaAntonella Tosti
Jul 25, 2015·Clinical and Experimental Dermatology·H MoravvejS Younespour
Dec 3, 2014·Clinical Lymphoma, Myeloma & Leukemia·Rakhshandra TalpurMadeleine Duvic
Dec 30, 2014·Annales de dermatologie et de vénéréologie·L Meunier
May 7, 2016·Journal of Cosmetic Dermatology·Marwa M T FawziOlfat Gamil Shaker
Sep 18, 2016·Clinics in Dermatology·Asta JuzenieneWilliam B Grant
Mar 24, 2016·Photodermatology, Photoimmunology & Photomedicine·Sikarin Upala, Anawin Sanguankeo
Oct 13, 2016·Indian Dermatology Online Journal·Ola Ahmed BakryAmira Soliman
Sep 25, 2016·Archives of Dermatological Research·Jordan M ThompsonEunyoung Cho
Oct 27, 2016·Journal of Dermatological Science·Teruki Dainichi, Kenji Kabashima
Jan 31, 2017·Dermatologic Therapy·Tarun NarangM Sendhil Kumaran
Oct 11, 2017·American Journal of Clinical Dermatology·Elio Kechichian, Khaled Ezzedine
Apr 11, 2018·Journal of the European Academy of Dermatology and Venereology : JEADV·S LeeW S Lee
May 24, 2018·The British Journal of Dermatology·F RajabiN Rezaei
Jul 19, 2017·Clinical Reviews in Allergy & Immunology·Ralph M Trüeb, Maria Fernanda Reis Gavazzoni Dias
Dec 16, 2017·International Journal of Dermatology·Manju DaroachMuthu Sendhil Kumaran
Apr 9, 2020·Dermatologic Therapy·Funda KemerizBurcu Tuğrul Ayanoğlu
Jun 10, 2020·International Journal of Dermatology·Sarita SankeRajeev Goyal
Jun 27, 2019·Archives of Dermatological Research·Moustafa A El TaiebManal Abualhamd
Jan 18, 2018·Journal of Cosmetic Dermatology·Zeynep Gizem Kaya İslamoğlu, Mehmet Unal
Jun 6, 2018·Clinical and Experimental Medicine·Venkata Krishna Vamsi GadeMedha Rajappa
Dec 8, 2017·International Journal of Molecular Sciences·Agnieszka GerkowiczGrażyna Chodorowska
Apr 28, 2017·Journal of Cosmetic Dermatology·Mehmet Unal, Gulsum Gonulalan
Jun 29, 2018·Scientific Reports·Ji Hyun LeeYoung Bok Lee
Dec 12, 2018·Clinical and Translational Allergy·Papapit TuchindaSutin Sriussadaporn
Dec 14, 2018·Dermatology and Therapy·Hind M AlmohannaAntonella Tosti
May 17, 2017·American Journal of Clinical Dermatology·Jordan M ThompsonEunyoung Cho
Dec 10, 2020·International Journal of Dermatology·Madeline J AdelmanGeoff A Potts
Jul 22, 2018·Journal of the American Academy of Dermatology·Solam LeeWon-Soo Lee
Apr 18, 2021·Anais Brasileiros De Dermatologia·Seshadri Reddy VarikasuvuAparna Varma Bhongir
Dec 5, 2019·Skin Appendage Disorders·Ralph M TrüebChuchai Tanglertsampan
Sep 4, 2018·International Journal of Women's Dermatology·N BrankovW F Bergfeld

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