Vitamin D deficiency is an independent risk factor for cardiovascular disease in Koreans aged ≥ 50 years: results from the Korean National Health and Nutrition Examination Survey.

Nutrition Research and Practice
Sunmin Park, Byung-Kook Lee

Abstract

Vitamin D deficiency is a risk factor for metabolic syndromes. We examined whether vitamin D deficiency altered the prevalence of cardiovascular disease (CVD) in older Koreans. Cross-sectional analysis of data from the Korean National Health and Nutrition Examination Survey IV 2008-2009 was used to examine the association between serum 25-hydroxyvitamin D (25(OH)D) levels and the prevalence of CVD in a representative population-based sample of 5,559 men and women aged ≥ 50 years. CVD was defined as angina pectoris, myocardial infarction, or stroke. The prevalence of CVD (7.0%) in the older Korean population was lower than that in the older US population, although average serum 25(OH)D levels were much lower in the Korean population. Additionally, serum 25(OH)D levels did not differ significantly between the CVD and non-CVD groups. However, subjects in the lowest category (< 25 nmol/l) of serum 25(OH)D level had the greatest prevalence of CVD, about two-fold higher than subjects in the highest category (> 75 nmol/l), after adjusting for age, gender, body mass index, education level, residence location, and region. The prevalence of other risk factors for CVD, including higher waist circumference, fasting glucose, low-density lip...Continue Reading

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Citations

Sep 11, 2012·Current Atherosclerosis Reports·Giovanni AnnuzziClaudia Vetrani
Mar 26, 2013·Journal of Clinical Biochemistry and Nutrition·Misung KimCheongmin Sohn
Apr 11, 2013·Journal of Preventive Medicine and Public Health = Yebang Ŭihakhoe Chi·Yangho KimByung-Kook Lee
Feb 6, 2016·International Journal of Environmental Research and Public Health·Kyung-Jin YeumNam-Seok Joo
Oct 22, 2013·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Sunmin ParkByung-Kook Lee
Feb 26, 2016·Archives of Endocrinology and Metabolism·Alexander ShinkovStefan Krivoshiev
May 29, 2013·The American Journal of Gastroenterology·Bijo K JohnJames S Scolapio
Aug 1, 2013·Medicine and Science in Sports and Exercise·Chang-Duk HaHyun-Sik Kang
Aug 17, 2012·Medicine and Science in Sports and Exercise·Chang-Duk HaHyun-Sik Kang
Jan 8, 2015·Journal of Exercise Nutrition & Biochemistry·Jinkook ParkHyunsik Kang
Aug 27, 2021·Journal of Cardiovascular Development and Disease·Gudrun FeuchtnerFabian Barbieri
Dec 29, 2016·The Journal of Steroid Biochemistry and Molecular Biology·Sunil J Wimalawansa

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