Vitamin D insufficiency in older female community-dwelling acute hospital admissions and the response to supplementation

European Journal of Clinical Nutrition
E DeLappeE Mulkerrin

Abstract

A significant proportion of the older population may exhibit vitamin D insufficiency. We sought to establish the proportion of 25-hydroxyvitamin D (25OHD) insufficient individuals in an older female cohort presenting for acute medical admission and how they responded to supplementation. A prospective cohort study. Hospital admissions followed up as a population-based study. A total of 114 consecutive female acute medical admissions aged over 65 years from November 2003 to January 2004 were enrolled. All admissions with hypercalcaemia, metabolic bone disease (other than osteoporosis/osteomalacia) and creatinine > 150 micromol/l were excluded. iPTH, calcium and 25OHD levels were measured in each patient. Of the total, 22 were already receiving calcium and vitamin D supplementation at enrolment. The remaining 92 were commenced on 800 IU of vitamin D and 1 g calcium, and levels were reassessed after supplementation for 3 months. 25-Hydroxyvitamin D insufficiency, as defined by a 25OHD concentration of < 50 nmol/l, was present in 86 (75.4%) patients at initial assessment (mean 35.8 nmol/l, s.d. 23.3). Secondary hyperparathyroidism was present in only 36.7% of those with 25OHD deficiency at baseline. Of the total, 51 (44.7%) patients...Continue Reading

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Citations

Aug 10, 2010·Irish Journal of Medical Science·G O'Malley, E Mulkerrin
Aug 18, 2010·Irish Journal of Medical Science·E LardnerE Mulkerrin
Nov 26, 2010·Nutrition Journal·Pankaj G VashiDigant Gupta
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Dec 1, 2017·The Journal of Nutrition, Health & Aging·J Delos ReyesE C Mulkerrin
Jan 24, 2020·Sudanese Journal of Paediatrics·Suad Mohamed AliElshazaly Saeed
Nov 6, 2007·Current Opinion in Endocrinology, Diabetes, and Obesity

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