Vitamin D3 and 25-hydroxyvitamin D3 in pork and their relationship to vitamin D status in pigs

Journal of Nutritional Science
Anders BurildJette Jakobsen

Abstract

The content of vitamin D in pork produced in conventional systems depends on the vitamin D concentration in the pig feed. Both vitamin D3 and 25-hydroxyvitamin D3 (25(OH)D3) are essential sources of dietary vitamin D; however, bioavailability assessed by serum 25(OH)D3 concentration is reported to be different between the two sources. Furthermore, the relationship between serum 25(OH)D3 level and the tissue content of vitamin D3 and 25(OH)D3 is unknown. The objective of this study was to investigate the potential of increasing the content of vitamin D in different pig tissues by increasing the levels of vitamin D3 and 25(OH)D3 in the pig feed for 49 d before slaughter. Concurrently, the 25(OH)D3 level in serum was investigated as a biomarker to assess the content of vitamin D3 and 25(OH)D3 in pig tissues. Adipose tissue, white and red muscle, the liver and serum were sampled from pigs fed feed containing either vitamin D3 or 25(OH)D3 at 5, 20, 35 or 50 µg/kg feed for 7 weeks before slaughter. The tissue 25(OH)D3 level was significantly higher in the pigs fed 25(OH)D3 compared with those fed vitamin D3, while the tissue vitamin D3 level was higher in the pigs fed vitamin D3 compared with those fed 25(OH)D3. The content of 25(OH)...Continue Reading

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Citations

Oct 25, 2016·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Angela CarrelliEmily M Stein
Nov 15, 2017·PloS One·D Enette Larson-MeyerBrenda M Alexander
May 1, 2019·Nutrients·Jette JakobsenKevin D Cashman
Aug 5, 2016·The American Journal of Clinical Nutrition·Aoife HayesKevin D Cashman
Oct 11, 2019·Current Developments in Nutrition·Jette JakobsenMichael Rychlik
Mar 18, 2020·Reviews in Endocrine & Metabolic Disorders·A GiustinaJ P Bilezikian
May 13, 2021·Current Developments in Nutrition·Matthew F Warren, Kimberly A Livingston
Jul 23, 2021·Critical Reviews in Food Science and Nutrition·Holly R NeillL Kirsty Pourshahidi

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