PMID: 9553906Apr 29, 1998Paper

Vitamin E: the radical protector

Journal of the European Academy of Dermatology and Venereology : JEADV
R WolfV Ruocco

Abstract

Since its discovery and isolation the importance of vitamin E in maintaining normal physiologic processes and its value in treating various disease states have been the subject of much controversy. It was our intention to review and highlight some of the arguments and problems regarding the usefulness of vitamin E and to try to put them into proper perspective. The major area of interest concerning vitamin E lies essentially in its role in preventing damage caused by free radicals. The latter are now known to play an important role in radiation induced carcinogenesis, photoaging and photosensitization. The chemistry of vitamin E, its physiological function as a major antioxidant and its interaction with other antioxidants are described by the sum of animal studies, in vitro research and epidemiological investigations. In preparing the current data, it appeared that despite the controversy and conflicting results the body of literature as a whole judges vitamin E to be useful as an antioxidant. Although, in principle, the use of vitamin E can be quite advantageous, the manner of its administration, especially regarding topical application, remains unclear.

Citations

May 18, 2005·Journal of Photochemistry and Photobiology. B, Biology·Helga MerwaldFranz Trautinger
Feb 24, 2001·Journal of the European Academy of Dermatology and Venereology : JEADV·T C Flynn, W P Coleman
Feb 25, 2010·Journal of Nanobiotechnology·Brian Sheng Xian TeoMohd Basyaruddin Abdul Rahman
Apr 15, 2010·The Journal of Organic Chemistry·Ryan WestJeffrey Atkinson
Feb 14, 2006·International Journal of Radiation Oncology, Biology, Physics·X Steven WanAnn R Kennedy
Sep 27, 2014·Life Sciences in Space Research·Ann R Kennedy
Jul 21, 2010·Toxicological Sciences : an Official Journal of the Society of Toxicology·Arati A InamdarJoan Wennstrom Bennett
Feb 13, 2001·Annual Review of Medicine·S C Textor, C S Wilcox

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