Abstract
A two way regression study was performed to investigate the interactions between vitamins C and E, and the influence of dietary vitamin C on the development of vitamin E deficiency in first feeding Atlantic salmon. The fish were fed three levels of all-rac-alpha-tocopheryl acetate (0, 150, and 300 mg/kg), each with six levels of ascorbate monophosphate (0, 7.5, 15, 30, 45, and 60 mg/kg ascorbic acid equivalents). Vitamin C protected the fish against vitamin E deficiency in a dose dependent manner, as seen from the data on growth, mortality, hematology, and lipid oxidation in the liver, indicated by the concentration of malondialdehyde. Vitamin C did not influence the tissue levels of vitamin E, except in vitamin C deficiency, which induced a large drop in liver vitamin E concentration. The liver level of vitamin C increased in response to supplementation of both vitamins. The results indicate two different interaction mechanisms: a synergistic effect of simultaneous protection of the water and lipid phases against oxidation, and regeneration of vitamin E from the vitamin E radical by ascorbic acid.
References
Oct 1, 1979·The Journal of Nutrition·K R RobbinsD H Baker
Apr 1, 1976·Biochemical Medicine·K Yagi
Nov 15, 1992·European Journal of Biochemistry·M E MurphyH Sies
Dec 1, 1992·The Biochemical Journal·V W BowryR Stocker
Jan 1, 1992·Free Radical Biology & Medicine·H Kappus, A T Diplock
Apr 19, 1991·Journal of Chromatography·O Lie, G Lambertsen
Sep 15, 1991·The Journal of Biological Chemistry·A C ChanC K Chow
Jun 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·J MãrtenssonJ Mrtensson
Feb 1, 1990·Analytical Biochemistry·A M SvardalP M Ueland
Apr 1, 1990·Lipids·G W BurtonK U Ingold
Aug 1, 1989·Lipids·M MaiorinoF Ursini
Jul 1, 1987·Chemistry and Physics of Lipids·E Niki
Jun 1, 1988·European Journal of Biochemistry·H Wefers, H Sies
Aug 1, 1969·The Journal of Nutrition·H H Draper, A S Csallany
Aug 15, 1984·Biochimica Et Biophysica Acta·J G BellA Youngson
Aug 1, 1980·Biochimica Et Biophysica Acta·H MehanshoL M Henderson
Oct 1, 1994·Free Radical Biology & Medicine·B S WinklerT S Rex
Nov 1, 1994·Chemico-biological Interactions·H J AndersenA L Tappel
Apr 21, 1994·Biochimica Et Biophysica Acta·A DemozR K Berge
Feb 1, 1993·Archives of Biochemistry and Biophysics·G R Buettner
Feb 16, 2012·Poultry Science·S TemelliK T Carli
Jul 1, 1994·Fish Physiology and Biochemistry·O LieR Waagbø
Jul 1, 1993·Fish Physiology and Biochemistry·R WaagbøK Sandnes
Oct 1, 1993·Fish Physiology and Biochemistry·R T Lochmann, D M Gatlin
Jan 1, 1994·Fish Physiology and Biochemistry·K HamreO Lie
Mar 1, 1994·Fish Physiology and Biochemistry·I ThompsonC J Secombes
Dec 1, 1992·Fish Physiology and Biochemistry·K SandnesR Waagbø
Nov 1, 1990·Fish Physiology and Biochemistry·K SandnesR Waagbø
Citations
Mar 8, 2000·BioFactors·K HamreO Lie
Oct 13, 2009·Fish Physiology and Biochemistry·Chhorn LimPhillip H Klesius
Oct 23, 2012·Lipids·Mónica B BetancorMarisol Izquierdo
Jun 8, 2001·Veterinary Immunology and Immunopathology·J OrtuñoJ Meseguer
Jun 14, 2002·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Giulia GuerrieroGaetano Ciarcia
Jun 15, 2010·The British Journal of Nutrition·Kristin HamreSissel Albrektsen
May 2, 2003·The British Journal of Nutrition·Kyeong-Jun Lee, Konrad Dabrowski
Aug 30, 2007·Journal of Zhejiang University. Science. B·Xiao-dong ZhangYong-fei Zhu
Jul 25, 2013·PeerJ·Kristin HamreOlav Breck
May 28, 2014·Poultry Science·T LuR A Dalloul
Mar 1, 2012·Fish & Shellfish Immunology·Qicun ZhouTuo Wang
Mar 8, 2011·Fish & Shellfish Immunology·Luca TacchiSamuel A M Martin
Feb 2, 2011·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Maria J DariasJose L Zambonino-Infante
Apr 27, 2010·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Janene L ThompsonKathryn A Schuller
Sep 15, 2009·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Tien-Sheng HuangBente E Torstensen
Sep 10, 2003·Journal of Fish Diseases·R WaagbøB Torstensen
Apr 24, 2009·Journal of Animal Physiology and Animal Nutrition·T L Welker, J L Congleton
Nov 22, 2012·Journal of Fish Diseases·M B BetancorM Izquierdo
Jan 12, 2012·Journal of Fish Diseases·A Oliva-Teles
Jun 11, 2014·Critical Reviews in Food Science and Nutrition·Cláudia AfonsoCarlos Cardoso
Aug 19, 2005·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·P A OlsvikM H G Berntssen
Aug 12, 2000·Fish & Shellfish Immunology·J OrtuñoJ Meseguer
Jan 16, 2003·Fish & Shellfish Immunology·J OrtuñoJ Meseguer
Oct 29, 2002·Fish & Shellfish Immunology·A CuestaJ Meseguer
Jan 10, 2017·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·K DaleS Ellingsen
Sep 17, 2004·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·G GuerrieroG Ciarcia
Nov 13, 2008·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Cristina E TrenzadoManuel de la Higuera
Jul 26, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Navideh AnarjanChin Ping Tan
Jun 23, 2006·Toxicological Sciences : an Official Journal of the Society of Toxicology·Victoria J Berdikova BohneAugustine Arukwe
May 10, 2019·Scientific Reports·Najlae El KertaouiPatrick Kestemont
Apr 2, 2002·The Journal of Nutrition·Wendy M Sealey, Delbert M Gatlin
Nov 18, 2018·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·R ChakrabartiP Mittal
Oct 15, 1998·The Journal of Nutrition·A C Chan
Apr 2, 1998·BioFactors·K F Gey
Jun 7, 2003·The American Journal of Clinical Nutrition·Kristina E HillRaymond F Burk
Nov 16, 2016·PeerJ·Kristin HamreGro-Ingunn Hemre
Jul 22, 2006·The Journal of Experimental Biology·P A OlsvikH Toften