Vitiligo: Clinical presentation and pathogenesis

Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete
M Schild, M Meurer

Abstract

Vitiligo is a chronic skin disorder with depigmentation of circumscribed areas due to structural and functional damage to melanocytes. There is international consensus on the classification in nonsegmental and segmental vitiligo. The influence of vitiligo on the quality of life is significant and is influenced by ethnic and sociocultural factors. There is a new insight into the genetic susceptibility, mechanisms and targets of the autoimmune inflammation, the altered morphology and function of melanocytes and into the association of vitiligo with other autoimmune diseases, skin cancer and skin cancer therapy. The recognition of associated autoimmune disorders is as important as is the assessment of changes in the quality of life. New insight into the pathogenesis may have therapeutic consequences. The relationship between vitiligo and skin cancer and between vitiligo and immunotherapies in patients with metastatic melanoma warrants close clinical monitoring of affected patients and further scientific studies.

References

Dec 1, 1991·The Journal of Investigative Dermatology·R HarningJ C Bystryn
Jan 1, 1991·Dermatologica·K U SchallreuterJ Berger
Feb 1, 1988·The British Journal of Dermatology·M Koga, T Tango
Aug 1, 1987·Archives of Dermatology·J C BystrynA Kopf
May 25, 1994·Biochimica Et Biophysica Acta·K U SchallreuterM Gütlich
Feb 1, 1996·The British Journal of Dermatology·A NorrisA J Thody
Nov 1, 1996·Journal of the American Academy of Dermatology·S K Hann, H J Lee
Mar 4, 2000·Journal of Dermatological Science·C S WuB N Wu
Aug 5, 2000·The Journal of Pathology·D J TobinK U Schallreuter
Nov 30, 2000·Archives of Physiology and Biochemistry·R LazarovaJ Shani
May 31, 2002·Dermatology : International Journal for Clinical and Investigative Dermatology·Karin U SchallreuterAngela Panske
Mar 8, 2003·Pigment Cell Research·Katia OngenaeJean-Marie Naeyaert
May 20, 2003·Pigment Cell Research·Asem AlkhateebRichard A Spritz
Jul 16, 2003·Pigment Cell Research·Yvon GauthierAlain Taïeb
May 14, 2004·Pigment Cell Research·Raymond E Boissy, Prashiela Manga
Dec 20, 2005·The Journal of Investigative Dermatology. Symposium Proceedings·Nikolas K Haass, Meenhard Herlyn
Jan 26, 2007·Pigment Cell Research·Alain TaïebUNKNOWN VETF Members
Jul 7, 2007·Journal of the American Board of Family Medicine : JABFM·Shalini G ForbisJohn M Pascoe
Sep 8, 2007·International Journal of Dermatology·George W M Millington, Nick J Levell
Apr 21, 2009·Journal of the American Academy of Dermatology·Camile L HexselHenry W Lim
Jul 31, 2009·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Mohamed M A E L SalemKarin U Schallreuter
Jan 27, 2010·Indian Journal of Dermatology·Rafael Falabella
Apr 17, 2010·European Journal of Dermatology : EJD·Paolo AmerioAntonio Tulli
Jun 16, 2010·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·K U Schallreuter, M M A E L Salem
Jun 29, 2010·Thyroid : Official Journal of the American Thyroid Association·Richard A Spritz
Jul 20, 2010·Transfusion Medicine·A M KuniyoshiJ O Bordin
Jan 20, 2011·International Journal of Dermatology·Sibel UncuKöksal Alpay
Jul 23, 2011·Allergology International : Official Journal of the Japanese Society of Allergology·Tomohiko NaritaTamio Suzuki
Aug 11, 2011·Archives of Dermatological Research·Amir Feily, Nader Pazyar
Sep 23, 2011·The British Journal of Dermatology·N van GeelR Speeckaert
Jan 31, 2012·Dermatologic Clinics·Sulochana S Bhandarkar, Roopal V Kundu
Mar 13, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·M W KroonR M Luiten
Mar 16, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·A PatriziI Neri
Mar 16, 2012·Pigment Cell & Melanoma Research·K EzzedineUNKNOWN Vitiligo Global Issue Consensus Conference Panelists
Mar 31, 2012·International Journal of Dermatology·Christian Krüger, Karin Uta Schallreuter
Apr 18, 2012·Archives of Dermatology·Khaled EzzedineAlain Taieb
May 12, 2012·Annals of Dermatology·Ai-Young Lee
Aug 7, 2012·The British Journal of Dermatology·A TaiebUNKNOWN Union Europe´enne des Me´decins Spe´cialistes (UEMS)
Aug 24, 2012·The British Journal of Dermatology·N van GeelL Brochez

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Citations

Feb 26, 2016·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·M Meurer, M Schild
Oct 17, 2017·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·M Meurer, P Ceric-Dehdari

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