Vitiligo improvement in a patient with ankylosing spondylitis treated with infliximab

Dermatology : International Journal for Clinical and Investigative Dermatology
J-Abraham Simón, Rubén Burgos-Vargas

Abstract

Ankylosing spondylitis (AS) is a disabling disease affecting the enthesis and joints of the spine and peripheral sites. Tumour necrosis factor alpha (TNF-alpha) is a proinflammatory mediator which plays a significant role in the pathogenesis of AS. Infliximab (a chimeric monoclonal antibody which blocks the activity of TNF-alpha) is one of the most effective therapies of AS thus far. Vitiligo is a depigmenting disorder of the skin of unknown aetiology affecting 0.5-1% of the population. Here we describe the effect of infliximab on vitiligo in a patient with AS.

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Citations

Aug 6, 2013·American Journal of Clinical Dermatology·Carlos R Camara-Lemarroy, Julio C Salas-Alanis
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Feb 20, 2020·Dermatology : International Journal for Clinical and Investigative Dermatology·Kalai Selvi RajendiranPanneer Devaraju

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