Vitiligoid variant of lichen sclerosus in young girls with darker skin types

Pediatric Dermatology
Margaret H DenninAdena E Rosenblatt

Abstract

Vitiligo and lichen sclerosus are autoimmune disorders characterized by white discoloration, and both frequently affect the anogenital region. Vitiligoid lichen sclerosus refers to a superficial variant of lichen sclerosus in which the lesion appears clinically to be vitiligo based on the predominant presentation of depigmentation and minimal inflammation and sclerosis but histologically is consistent with lichen sclerosus. A limited number of reports have described vitiligoid lichen sclerosus, and from these reports, it appears to primarily affect darker-skinned people. We retrospectively reviewed the records of 7 girls with darker skin types seen in our pediatric dermatology clinic who presented with a clinical overlap of vitiligo and lichen sclerosus. All had primarily well-demarcated, depigmented patches characteristic of vitiligo, but the lesions were symptomatic (pruritus, pain, bleeding, constipation), a presentation more consistent with lichen sclerosus. The girls were all treated with high-potency topical steroids, calcineurin inhibitors, or both. The associated symptoms improved or resolved, but most had minimal improvement of the depigmentation. The girls presented in this series appear to have had vitiligoid lichen ...Continue Reading

References

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Citations

Nov 5, 2019·Pediatric Dermatology·Jacquelyn R Sink, Nanette B Silverberg
Sep 19, 2019·Pediatric Dermatology·Pooja R ShahMaria Cordisco
Aug 23, 2019·Journal of the American Academy of Dermatology·Beth MorrelSuzanne G M A Pasmans
Sep 26, 2021·Pediatric Dermatology·Giulia VeronesiIria Neri

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