Vitreous and Vision Degrading Myodesopsia.

Progress in Retinal and Eye Research
J Sebag

Abstract

Macromolecules comprise only 2% of vitreous, yet are responsible for its gel state, transparency, and physiologic function(s) within the eye. Myopia and aging alter collagen and hyaluronan association causing concurrent gel liquefaction and fibrous degeneration. The resulting vitreous opacities and collapse of the vitreous body during posterior vitreous detachment are the most common causes for the visual phenomenon of vitreous floaters. Previously considered innocuous, the vitreous opacities that cause floaters sometimes impact vision by profoundly degrading contrast sensitivity function and impairing quality-of-life. While many people adapt to vitreous floaters, clinically significant cases can be diagnosed with Vision Degrading Myodesopsia based upon echographic assessment of vitreous structure and by measuring contrast sensitivity function. Perhaps due to the ubiquity of floaters, the medical profession has to date largely ignored the plight of those with Vision Degrading Myodesopsia. Improved diagnostics will enable better disease staging and more accurate identification of severe cases that merit therapy. YAG laser treatments may occasionally be slightly effective, but vitrectomy is currently the definitive cure. Future d...Continue Reading

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Citations

Jan 9, 2021·Ophthalmology Retina·J Sebag
Jan 8, 2021·Experimental Eye Research·Priscilla Sayami AkamineDânia Emi Hamassaki
Sep 21, 2020·American Journal of Ophthalmology·Justin H NguyenJ Sebag
Apr 28, 2021·Nanoscale Horizons : the Home for Rapid Reports of Exceptional Significance in Nanoscience and Nanotechnolgy·Alexandre BarrasSabine Szunerits
May 1, 2021·Investigative Ophthalmology & Visual Science·Daniel RuminskiIreneusz Grulkowski

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