Vocal outcome measures after bilateral posterior cricoarytenoid muscle botulinum toxin injections for abductor spasmodic dysphonia

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
Adam M KleinMichael M Johns

Abstract

To review vocal outcome measures, using the Voice Related Quality of Life (VRQOL) index, after simultaneous bilateral posterior cricoarytenoid muscle botulinum toxin injections. Case series. Tertiary care academic clinic. Fourteen subjects with abductor spasmodic dysphonia received 37 simultaneous bilateral posterior cricoarytenoid muscle botulinum toxin injections for isolated abductor spasmodic dysphonia (ABSD) over a 16-month period. VRQOL index. Of the 37 injections, 33 of 37 (89%) resulted in improvement. Three injections resulted in no improvement, and one injection resulted in a worse VRQOL. The overall VRQOL mean improvement was 19.8 (range 5-53), with an average pre/postinjection VRQOL interval of 36 days (range 21-45 days). Simultaneous bilateral posterior cricoarytenoid muscle botulinum injections result in a statistically significant improvement in VRQOL index scores for a high percentage of ABSD patients, thus improving patient quality of life.

References

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Citations

Jul 25, 2009·HNO·E GrässelF Rosanowski
May 27, 2009·Current Opinion in Otolaryngology & Head and Neck Surgery·Jeffrey M Ulis, Eiji Yanagisawa
Apr 2, 2009·Current Opinion in Otolaryngology & Head and Neck Surgery·Christy L Ludlow
Jul 2, 2009·Plastic and Reconstructive Surgery·Michael W NeumeisterCarisa M Cooney
Feb 6, 2014·Journal of Voice : Official Journal of the Voice Foundation·Robbi A KupferNorman D Hogikyan
Jun 17, 2014·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·R MandaviaA D'Souza
Aug 16, 2016·Journal of Voice : Official Journal of the Voice Foundation·Wonjae ChaMin-Gyu Jo
Nov 4, 2017·Toxins·Rachel Kaye, Andrew Blitzer
Apr 16, 2018·Journal of Voice : Official Journal of the Voice Foundation·Anna RumbachDaniel Novakovic

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Methods Mentioned

BETA
PCA

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Botulism (ASM)

Botulism is a rare but serious paralytic illness caused by a nerve toxin that is produced by the bacterium clostridium botulinum. Discover the latest research on botulism here.

Botulism

Botulism is a rare but serious paralytic illness caused by a nerve toxin that is produced by the bacterium clostridium botulinum. Discover the latest research on botulism here.

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