Volatile compounds of Lamiaceae exhibit a synergistic antibacterial activity with streptomycin

Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]
Sthéfane G AraújoLuciana A R S Lima

Abstract

Bacterial infections cause thousands of deaths in the world every year. In most cases, infections are more serious because the patient is already weakened, and often, the bacteria are already resistant to the antibiotics used. Counterparting this negative scenario, the interest in medicinal plants as an alternative to the synthetic antimicrobial drugs is blossoming worldwide. In the present work, we identified the volatile compounds of ethanol extracts of Melissa officinalis, Mentha sp., Ocimum basilicum, Plectranthus barbatus, and Rosmarinus officinalis by gas chromatography/mass spectrometry (GC/MS). Also was evaluated antimicrobial activity of ethanol extracts against 6 bacteria of clinical interest, and was tested the interaction of these extracts with a commercial antibiotic streptomycin. Phytol was a compound identified in all extracts by GC/MS, being majoritary component in Plectranthus barbatus and Rosmarinus officinalis. The Gram-positive bacteria were more sensitive to ethanol extracts, and Plectranthus barbatus and Rosmarinus officinalis were the most active extracts. Ethanol extracts exhibited a synergetic effect with streptomycin. These results encourage additional studies, in order to evaluate the possibilities of...Continue Reading

Citations

Apr 19, 2018·Anais Da Academia Brasileira De Ciências·Felipe V DE AssisJaqueline M S Ferreira
Apr 1, 2021·Brazilian Journal of Biology = Revista Brasleira De Biologia·M F CordeiroM J B M Rêgo

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