PMID: 9159507Apr 25, 1997Paper

Voltammetric detection of nitric oxide (NO) in the rat brain: its variations throughout the sleep-wake cycle

Neuroscience Letters
S Burlet, Raymond Cespuglio

Abstract

A sensor allowing the specific detection of nitric oxide (NO) is reported. Together with differential pulsed voltammetry, it allows the detection of a 650 mV signal either in NO solutions or in the rat frontal cortex. The intraperitoneal (i.p.) administration of a NO donor (S-nitrosoglutathione, 20 mg/kg i.p.) increases the signal height (+30%) while that of a nitric oxide synthase (NOS) inhibitor like L-nitro-arginine-p-nitro-anilide (100 mg/kg i.p.), produces its complete disappearance in the cortex of anesthetized rats. These results suggest that the 650 mV signal might be NO-dependent. Some other NOS inhibitors have been found either inefficient (L-nitro-arginine-methyl-ester) or partially efficient (7-nitro-indazole) on the signal height. In freely moving rats, also equipped with polygraphic electrodes, the signal measured in the frontal cortex exhibits the highest height during waking. It decreases during slow-wave sleep (-6%) and paradoxical sleep (-9%).

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Citations

Jul 29, 2008·Psychopharmacology·Andrey KostinTarja Porkka-Heiskanen
Mar 2, 2005·Sleep Medicine Reviews·Sabine Gautier-SauvignéRaymond Cespuglio
Mar 16, 2000·Transactions of the Royal Society of Tropical Medicine and Hygiene·A BuguetR Cespuglio
Aug 8, 2001·Journal of Neuroscience Methods·F CrespiL Cominacini
Sep 27, 2002·Journal of Neuroscience Methods·Manuel MasJose Luis Gonzalez-Mora
Oct 9, 1999·Progress in Neurobiology·C Gottesmann
Aug 8, 1997·Neuroscience Letters·F CaniniA Buguet
Aug 21, 2003·Burns : Journal of the International Society for Burn Injuries·Philippe LestaevelYves Chancerelle
Jul 17, 1999·Neuroscience·S BurletR Cespuglio
Apr 12, 2001·The European Journal of Neuroscience·L NetchiporoukR Cespuglio
Jul 18, 2000·Epilepsia·H FaradjiR Cespuglio
Jul 20, 2012·Physiological Reviews·Ritchie E BrownRobert W McCarley
Mar 13, 2012·Sleep Medicine Reviews·Raymond CespuglioSabine Gautier-Sauvigné
Mar 6, 1999·The Journal of Physiology·A EscrigM Mas
Feb 6, 2007·Progress in Neuro-psychopharmacology & Biological Psychiatry·Monica L AndersenSergio Tufik
Sep 22, 2006·The European Journal of Neuroscience·A V KalinchukT Porkka-Heiskanen
Oct 13, 2006·Journal of Neurochemistry·A V KalinchukT Porkka-Heiskanen
Aug 14, 2009·Journal of Sleep Research·Andrey KostinTarja Porkka-Heiskanen
Aug 18, 2004·Progress in Neurobiology·Radhika BasheerRobert W McCarley
Sep 19, 2006·Respiratory Physiology & Neurobiology·Daniel J O'HearnWilliam E Holden
Jul 19, 2005·Progress in Neuro-psychopharmacology & Biological Psychiatry·María Cavas, José Francisco Navarro
Nov 8, 2014·Fundamental & Clinical Pharmacology·Yue CuiGang Liu
Jan 18, 2003·Sleep Medicine Reviews·A BuguetM Dumas
Aug 27, 2004·Journal of Dental Research·T C B SchützS Tufik
Apr 30, 2005·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Ana C Ribeiro, Levente Kapás
Nov 9, 2018·Frontiers in Cellular Neuroscience·Maia DatunashviliThomas Budde
Apr 6, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·A C RibeiroL Kapás
Feb 19, 2021·Biosensors & Bioelectronics·Shuang ZhaoGuixue Wang

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