PMID: 38680May 1, 1979

Volume and pH of gastric contents following anticholinergic premedication

Anaesthesia
R K MirakhurJ Elliott

Abstract

The effects of anticholinergic premedication with 1.0 mg atropine, 0.5 mg hyoscine and 0.2 mg glycopyrronium on volume and pH of gastric contents were studied and compared with a group receiving no anticholinergic premedication. The antisialogogue effects were also compared. Though the groups receiving atropine and glycopyrronium had the lowest mean aspirated volume and the highest mean pH respectively there was no essential difference between the various groups receiving anticholinergic premedication. However, the pH values were above 2.5 in the majority of these patients in comparison with the control group. The antisialogogue effects of the three anticholinergic drugs were similar.

References

Jun 1, 1977·British Journal of Anaesthesia·J B Hester, M L Heath
Sep 1, 1977·Anesthesia and Analgesia·A BarakaA P Winnie
Jan 1, 1978·Canadian Anaesthetists' Society Journal·B Y OngM Cumming
Jan 1, 1978·British Journal of Clinical Pharmacology·R K MirakhurC J Jones
Feb 1, 1978·Anaesthesia·R K MirakhurJ R McDonald
Mar 1, 1978·Canadian Anaesthetists' Society Journal·J G Brock-UtneJ W Downing
Jun 1, 1978·British Journal of Anaesthesia·R K Mirakhur
Nov 1, 1973·British Journal of Anaesthesia·S K LahiriR M Hodgson
Jan 1, 1970·British Journal of Anaesthesia·J S Crawford
Mar 1, 1968·Canadian Journal of Physiology and Pharmacology·J F LindD K McIver
Nov 25, 1965·The New England Journal of Medicine·L D Vandam
Oct 1, 1958·The American Journal of Digestive Diseases·W H BACHRACH
Nov 1, 1959·British Journal of Anaesthesia·R G SNOW, J F NUNN
Mar 1, 1962·Anesthesiology·W K BANNISTER, A J SATTILARO
Feb 28, 1962·Annals of the New York Academy of Sciences·R YOUNG, D C SUN
Aug 1, 1946·American Journal of Obstetrics and Gynecology·C L MENDELSON

Citations

Sep 1, 1996·Journal of Clinical Anesthesia·C A BernsteinD Ritter
Feb 10, 2006·Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine·D M BurgerS Arnold
Dec 1, 1982·Acta Anaesthesiologica Scandinavica·F Kongsrud, S Sponheim
Dec 1, 1983·Anaesthesia·R K Mirakhur, J W Dundee

Related Concepts

Atropen
Clinical Trials
Double-Blind Method
Gastric Juice
Glycopyrrolate
Hydrogen-Ion Concentration
Antispasmodic Effect
Placebos
Preanesthetic Medication
Randomization

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