PMID: 38680May 1, 1979

Volume and pH of gastric contents following anticholinergic premedication

R K MirakhurJ Elliott


The effects of anticholinergic premedication with 1.0 mg atropine, 0.5 mg hyoscine and 0.2 mg glycopyrronium on volume and pH of gastric contents were studied and compared with a group receiving no anticholinergic premedication. The antisialogogue effects were also compared. Though the groups receiving atropine and glycopyrronium had the lowest mean aspirated volume and the highest mean pH respectively there was no essential difference between the various groups receiving anticholinergic premedication. However, the pH values were above 2.5 in the majority of these patients in comparison with the control group. The antisialogogue effects of the three anticholinergic drugs were similar.


Jun 1, 1977·British Journal of Anaesthesia·J B Hester, M L Heath
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Jan 1, 1978·Canadian Anaesthetists' Society Journal·B Y OngM Cumming
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Jun 1, 1978·British Journal of Anaesthesia·R K Mirakhur
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Feb 28, 1962·Annals of the New York Academy of Sciences·R YOUNG, D C SUN
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Sep 1, 1996·Journal of Clinical Anesthesia·C A BernsteinD Ritter
Feb 10, 2006·Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine·D M BurgerS Arnold
Dec 1, 1982·Acta Anaesthesiologica Scandinavica·F Kongsrud, S Sponheim
Dec 1, 1983·Anaesthesia·R K Mirakhur, J W Dundee

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