PMID: 26784555Jan 20, 2016Paper

Volumetric analysis of aneurysm thrombosis after thoracic endovascular aortic repair predicts postoperative changes in platelet count and coagulation parameters

The Journal of Cardiovascular Surgery
Andrea KahlbergR Chiesa

Abstract

To investigate the predictors of blood count changes and coagulation parameters alterations after thoracic aortic endovascular repair (TEVAR). 50 patients (41 males, age 72 ± 7 years) submitted between 2007 and 2009 to elective TEVAR for non-dissecting aortic lesions, without major associated surgical procedures, were analyzed. Blood count and coagulation parameters were recorded pre-operatively and daily up to postoperative day 5. The volume of new thrombus formed after TEVAR (TV) was calculated comparing pre- and post-operative computed tomography scans with a semi-automatic method by two independent examiners. Pre- intra-, and post-operative variables, including TV, were tested for a possible effect on changes in laboratory values and transfusion requirements using a stepwise multiple regression model analysis. In the multivariable model, TV and associated surgical procedures were significantly associated with maximum platelets decrease (P = 0.021, and P = 0.029, respectively), while only TV remained a significant predictor for maximum prothrombin time increase (P = 0.003). Maximum aneurysm diameter (P = 0.041), procedural time (P = 0.027), and TV (P = 0.047) were also significant predictors of transfusion requirement. TEVAR...Continue Reading

Citations

Jul 1, 2021·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Rodolfo PiniMauro Gargiulo

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