Volumetric quantification of bone-implant contact using micro-computed tomography analysis based on region-based segmentation

Imaging Science in Dentistry
Sung-Won KangWon-Jin Yi

Abstract

We have developed a new method of segmenting the areas of absorbable implants and bone using region-based segmentation of micro-computed tomography (micro-CT) images, which allowed us to quantify volumetric bone-implant contact (VBIC) and volumetric absorption (VA). The simple threshold technique generally used in micro-CT analysis cannot be used to segment the areas of absorbable implants and bone. Instead, a region-based segmentation method, a region-labeling method, and subsequent morphological operations were successively applied to micro-CT images. The three-dimensional VBIC and VA of the absorbable implant were then calculated over the entire volume of the implant. Two-dimensional (2D) bone-implant contact (BIC) and bone area (BA) were also measured based on the conventional histomorphometric method. VA and VBIC increased significantly with as the healing period increased (p<0.05). VBIC values were significantly correlated with VA values (p<0.05) and with 2D BIC values (p<0.05). It is possible to quantify VBIC and VA for absorbable implants using micro-CT analysis using a region-based segmentation method.

References

Nov 1, 1966·Archives of Surgery·R K KulkarniF Leonard
Dec 22, 1999·Journal of Biomedical Materials Research·P LaffargueX Marchandise
Dec 25, 2002·The Journal of Oral Implantology·Maurizio PiattelliAdriano Piattelli
Sep 3, 2004·The Journal of Prosthetic Dentistry·Jeffrey L Tarlow
Mar 22, 2005·Clinical Oral Implants Research·Young-Seok ParkYoung-Chul Jung
Jun 14, 2006·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·Toru DeguchiTeruko Takano-Yamamoto
Jun 26, 2007·Clinical Oral Implants Research·Kurt SchichoRolf Ewers
Nov 6, 2008·Clinical Oral Implants Research·Laurent Le GuehennecPierre Layrolle
Apr 12, 2012·European Cells & Materials·Ricardo BernhardtBernd Stadlinger

❮ Previous
Next ❯

Citations

Jan 18, 2017·Journal of Tissue Engineering and Regenerative Medicine·Siddharth ShanbhagAndreas Stavropoulos
Jul 1, 2020·Imaging Science in Dentistry·Fernanda Ferrari Esteves TorresMário Tanomaru-Filho
Jul 3, 2021·Journal of Functional Biomaterials·Maria Fernanda Lima Villaça-CarvalhoLuana Marotta Reis de Vasconcellos

❮ Previous
Next ❯

Methods Mentioned

BETA
acid etching

Software Mentioned

SPSS
ScopeEye

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.