Voluntary activation and cortical activity during a sustained maximal contraction: an fMRI study.

Human Brain Mapping
Marijn PostInge Zijdewind

Abstract

Motor fatigue is an exercise-induced reduction in the force-generating capacity. The underlying mechanisms can be separated into factors residing in the periphery or in the central nervous system. We designed an experiment in which we investigated central processes underlying motor fatigue by means of magnetic resonance imaging in combination with the twitch interpolation technique. Subjects performed a sustained maximal abduction (2 min) with the right index finger. Brain activation was recorded with an MR scanner, together with index finger abduction force, EMG of several hand muscles and interpolated twitches. Mean activity per volume was calculated for the primary motor cortex and the secondary motor areas (supplementary motor, premotor, and cingulate areas) as well as mean force and mean rectified EMG amplitude. Results showed a progressive decline in maximal index finger abduction force and EMG of the target muscles combined with an increase in brain activity in the contralateral primary motor cortex and secondary motor areas. Analysis of the twitches superimposed on the sustained contraction revealed that during the contraction the voluntary drive decreased significantly. In conclusion, our data showed that despite an in...Continue Reading

References

May 1, 1992·Journal of Applied Physiology·R M Enoka, D G Stuart
Jan 1, 1990·European Journal of Applied Physiology and Occupational Physiology·C ZijdewindD Kernell
Nov 1, 1989·Journal of Applied Physiology·C K ThomasB Bigland-Ritchie
Jul 1, 1989·The Journal of Physiology·A Hicks, A J McComas
Jun 1, 1989·Journal of Applied Physiology·A HicksA J McComas
Nov 1, 1981·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·A Y Belanger, A J McComas
Nov 1, 1981·Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology·B Bigland-RitchieC S Roussos
Aug 1, 1995·Journal of Neurophysiology·C DettmersR S Frackowiak
Jan 1, 1994·Physiological Reviews·R H Fitts
Jan 15, 1996·The Journal of Physiology·J L TaylorS C Gandevia
Mar 1, 1996·The Journal of Physiology·C M CupidoA J McComas
Sep 2, 1996·Neuroreport·C DettmersR S Frackowiak
Dec 24, 1997·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·L LemieuxD R Fish
Aug 11, 1998·Experimental Brain Research·G W ThickbroomF L Mastaglia
May 16, 2001·Journal of Neurophysiology·I Zijdewind, D Kernell
Jul 13, 2001·Nature·N K LogothetisA Oeltermann
Oct 3, 2001·Physiological Reviews·S C Gandevia
Nov 26, 2002·Brain Research·Jing Z LiuGuang H Yue
Nov 26, 2002·Trends in Neurosciences·David Attwell, Costantino Iadecola
Aug 9, 2003·European Journal of Applied Physiology·Maartje L SchillingsMachiel J Zwarts
Mar 29, 1954·The Journal of Physiology·P A MERTON
Oct 8, 2003·Proceedings of the National Academy of Sciences of the United States of America·Jean-Yves ChattonPierre J Magistretti
Nov 4, 2005·Journal of Neurophysiology·David E VaillancourtDaniel M Corcos
Mar 25, 2006·The Journal of Physiology·Karen SøgaardJanet L Taylor
Apr 6, 2007·NeuroImage·Hiske van DuinenInge Zijdewind
Jun 6, 2007·Experimental Brain Research·Nicola M BenwellGary W Thickbroom
Jul 3, 2007·Journal of Neuroscience Methods·Hiske van DuinenInge Zijdewind

❮ Previous
Next ❯

Citations

Mar 13, 2012·Brain : a Journal of Neurology·Marc L OttenGuy M McKhann
Dec 27, 2011·NeuroImage·Zhiguo JiangGuang H Yue
Oct 1, 2015·The Journal of Physiological Sciences : JPS·Masaaki TanakaYasuyoshi Watanabe
Apr 24, 2012·Biometrical Journal. Biometrische Zeitschrift·Xiao-Feng Wang
May 7, 2015·Scandinavian Journal of Medicine & Science in Sports·B RoelandsR Meeusen
Feb 12, 2014·Brain Research·Masaaki TanakaYasuyoshi Watanabe
Nov 2, 2011·Neuroscience and Biobehavioral Reviews·Masaaki Tanaka, Yasuyoshi Watanabe
Mar 7, 2014·Medical Hypotheses·Masaaki TanakaYasuyoshi Watanabe
May 9, 2014·Frontiers in Aging Neuroscience·Ria WolkorteInge Zijdewind
Oct 21, 2016·Experimental Brain Research·Kazuhiro SugawaraShigeki Kameyama
Oct 8, 2014·Neurorehabilitation and Neural Repair·Ria WolkorteInge Zijdewind
Oct 19, 2016·Medicine and Science in Sports and Exercise·Janet L TaylorCharles L Rice
Jul 29, 2016·Exercise and Sport Sciences Reviews·Inge ZijdewindRia Wolkorte
Oct 19, 2016·Medicine and Science in Sports and Exercise·Roger M Enoka, Jacques Duchateau
May 24, 2013·Medicine and Science in Sports and Exercise·Benjamin PageauxRomuald Lepers
Nov 15, 2017·Scandinavian Journal of Medicine & Science in Sports·X R TanJ K W Lee
Jun 14, 2014·Reviews in the Neurosciences·Akira IshiiYasuyoshi Watanabe
Oct 12, 2013·Reviews in the Neurosciences·Masaaki TanakaYasuyoshi Watanabe
May 3, 2013·Journal of Neurophysiology·Justin J KavanaghTimothy J Carroll
Sep 13, 2013·Journal of Neurophysiology·Ela B PlowGuang H Yue
Nov 7, 2015·Behavioral and Brain Functions : BBF·Masaaki TanakaYasuyoshi Watanabe
Dec 20, 2018·Journal of Neurophysiology·Lavender A OtienoSimranjit K Sidhu
Jun 20, 2019·Frontiers in Integrative Neuroscience·Zheng WangMatthew W Mosconi
Jun 4, 2020·BMC Neuroscience·Oliver Seidel-Marzi, Patrick Ragert
Feb 10, 2012·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Samuel VergesGuillaume Y Millet
Jan 1, 2013·Brain Sciences·Stephane Perrey
Jun 30, 2021·The European Journal of Neuroscience·David Colomer-PovedaTibor Hortobágyi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.