PMID: 18717115Aug 23, 2008Paper

Voluntary respiratory control and cerebral blood flow velocity upon ice-water immersion

Aviation, Space, and Environmental Medicine
Teit MantoniFrank C Pott

Abstract

In non-habituated subjects, cold-shock response to cold-water immersion causes rapid reduction in cerebral blood flow velocity (approximately 50%) due to hyperventilation, increasing risk of syncope, aspiration, and drowning. Adaptation to the response is possible, but requires several cold immersions. This study examines whether thorough instruction enables non-habituated persons to attenuate the ventilatory component of cold-shock response. There were nine volunteers (four women) who were lowered into a 0 degrees C immersion tank for 60 s. Middle cerebral artery mean velocity (CBFV) was measured together with ventilatory parameters and heart rate before, during, and after immersion. Within seconds after immersion in ice-water, heart rate increased significantly from 95 +/- 8 to 126 +/- 7 bpm (mean +/- SEM). Immersion was associated with an elevation in respiratory rate (from 12 +/- 3 to 21 +/- 5 breaths, min(-1)) and tidal volume (1022 +/- 142 to 1992 +/- 253 ml). Though end-tidal carbon dioxide tension decreased from 4.9 +/- 0.13 to 3.9 +/- 0.21 kPa, CBFV was insignificantly reduced by 7 +/- 4% during immersion with a brief nadir of 21 +/- 4%. Even without prior cold-water experience, subjects were able to suppress reflex hy...Continue Reading

Citations

Nov 2, 2016·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Sarah AndersonDavid B Thorp
Jun 27, 2017·The Journal of Physiology·Michael J TiptonJoseph T Costello
Nov 23, 2013·Journal of Applied Physiology·R V ImminkJ J van Lieshout
Jan 30, 2015·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Bun TsujiTakeshi Nishiyasu
Feb 19, 2016·Physiology·Joost J L M BierensDavid S Warner
Dec 3, 2020·Frontiers in Neurology·Matthew D GarveyTeena Shetty

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