Voxel-wise quantification of myocardial perfusion by cardiac magnetic resonance. Feasibility and methods comparison.

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
Niloufar ZarinabadEike Nagel

Abstract

The purpose of this study is to enable high spatial resolution voxel-wise quantitative analysis of myocardial perfusion in dynamic contrast-enhanced cardiovascular MR, in particular by finding the most favorable quantification algorithm in this context. Four deconvolution algorithms--Fermi function modeling, deconvolution using B-spline basis, deconvolution using exponential basis, and autoregressive moving average modeling--were tested to calculate voxel-wise perfusion estimates. The algorithms were developed on synthetic data and validated against a true gold-standard using a hardware perfusion phantom. The accuracy of each method was assessed for different levels of spatial averaging and perfusion rate. Finally, voxel-wise analysis was used to generate high resolution perfusion maps on real data acquired from five patients with suspected coronary artery disease and two healthy volunteers. On both synthetic and perfusion phantom data, the B-spline method had the highest error in estimation of myocardial blood flow. The autoregressive moving average modeling and exponential methods gave accurate estimates of myocardial blood flow. The Fermi model was the most robust method to noise. Both simulations and maps in the patients an...Continue Reading

References

Dec 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·H Gudbjartsson, S Patz
May 1, 1996·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·H B LarssonO Henriksen
Apr 28, 2000·Biometrics·J K LindseyB Jones
May 30, 2002·Medical Physics·Michael Jerosch-HeroldRavi Teja Seethamraju
Jul 12, 2002·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Bruno NeyranEmmanuelle P Canet Soulas
Apr 22, 2003·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·E V R Di BellaC J McGann
Jun 2, 2004·Journal of Magnetic Resonance Imaging : JMRI·Michael Jerosch-HeroldArthur E Stillman
Feb 8, 2006·Journal of Magnetic Resonance Imaging : JMRI·Li-Yueh HsuAndrew E Arai
Jan 5, 2007·Physics in Medicine and Biology·S SourbronR Luypaert
Sep 28, 2007·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Sven PleinSebastian Kozerke
Jul 29, 2008·Medical Image Analysis·Stephen L KeelingRudolf Stollberger
Nov 19, 2008·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Nathan A PackJohn M Hoffman
Apr 9, 2009·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Takashi IchiharaHajime Sakuma
Jun 13, 2009·JACC. Cardiovascular Imaging·Daniel C Lee, Nils P Johnson
Jun 26, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Nathan A Pack, Edward V R DiBella
Aug 4, 2010·Physics in Medicine and Biology·Jeny RajanJan Sijbers
Oct 12, 2010·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Michael Jerosch-Herold
Mar 12, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Huijun ChenWilliam S Kerwin
May 26, 2011·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Masaki IshidaEike Nagel
Feb 1, 1982·IEEE Transactions on Pattern Analysis and Machine Intelligence·R L Kashyap

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Citations

Jan 28, 2014·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Christopher A MillerMatthias Schmitt
Jan 16, 2016·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Adriana D M VillaAmedeo Chiribiri
Dec 26, 2015·European Heart Journal Cardiovascular Imaging·Amedeo ChiribiriEike Nagel
Dec 8, 2015·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Lukas WissmannSebastian Kozerke
Oct 16, 2014·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Andreas SchusterEike Nagel
Aug 22, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Bastiaan J van NieropGustav J Strijkers
May 23, 2014·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Niloufar ZarinabadEike Nagel
Apr 17, 2015·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Eva SammutAmedeo Chiribiri
Jan 28, 2017·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Lukas WissmannSebastian Kozerke
Mar 9, 2018·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Allison D TaAndrew E Arai
May 20, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Xenios MilidonisAmedeo Chiribiri
Feb 8, 2020·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Melanie T P LeValentina O Puntmann
Feb 17, 2017·Journal of Magnetic Resonance Imaging : JMRI·Mitchel BenovoyLi-Yueh Hsu
Jan 1, 2017·European Journal of Hybrid Imaging·Jim O'DohertyAmedeo Chiribiri
Dec 20, 2017·Physics in Medicine and Biology·Cristian BorrazzoIacopo Carbone
Nov 21, 2018·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Adriana D M VillaAmedeo Chiribiri
Oct 30, 2018·Physics in Medicine and Biology·Judith LehnertClemens Elster
Mar 5, 2020·European Radiology Experimental·Marije E KamphuisCornelis H Slump

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