Vulnerability factors for common mental illnesses

The British Journal of Psychiatry. Supplement
D P Goldberg

Abstract

Twin studies suggest that shared early family environment is of only minor importance in the aetiology of depression, most of the variance being attributable either to genetic or to individual 'non-shared' environmental factors. To examine the respective roles of personality and social experiences on the risk for common mental disorders, with special reference to depression. Analysis of preliminary findings from two large-scale British population surveys: (a) a multi-centre study of general practice patients, and (b) a study of working-class women in Manchester. (a) Persons recently separated from their partners have raised mean scores for psychological distress, but the relative excess is due entirely to persons with high ratings for introversion; (b) while severe life events were associated with physiological responses characteristic of depression, the probability of experiencing such life events varied between 0.2 monthly for low scorers and 1.5 monthly for high scorers on a vulnerability measure. Social factors do appear to influence the prevalence of depression, but this effect is not independent of genetically determined vulnerability.

References

Apr 1, 1992·Archives of General Psychiatry·K S KendlerL J Eaves
Jan 1, 1990·Psychological Medicine. Monograph Supplement·P Duncan-JonesL J Horwood
Dec 1, 1990·Journal of Personality and Social Psychology·L R Goldberg
May 1, 1987·Archives of General Psychiatry·K S KendlerL J Eaves
Jan 1, 1986·Social Psychiatry. Sozialpsychiatrie. Psychiatrie Sociale·L J Horwood, D M Fergusson
Jun 1, 1995·The American Journal of Psychiatry·K S KendlerL J Eaves
Jan 1, 1997·Journal of Personality and Social Psychology·K J SaudinoR Plomin
Aug 26, 1998·Social Psychiatry and Psychiatric Epidemiology·G W Brown
Apr 2, 1999·Journal of Child Psychology and Psychiatry, and Allied Disciplines·M RutterE Simonoff
Jul 10, 1999·Journal of Abnormal Child Psychology·T C Eley, J Stevenson

❮ Previous
Next ❯

Citations

May 15, 2002·Psychiatry Research·Alec Roy
Sep 11, 2002·Social Science & Medicine·Richard ThomasBrian Robson
Sep 17, 2004·Ethnicity & Health·Dannette MarieLynden K Miles
May 2, 2003·The Journal of the American Academy of Psychoanalysis and Dynamic Psychiatry·John Read, Colin A Ross
Apr 27, 2012·European Psychiatry : the Journal of the Association of European Psychiatrists·L ChatziM Kogevinas
May 1, 2010·European Psychiatry : the Journal of the Association of European Psychiatrists·G B Ploubidis, S Frangou
Jan 14, 2005·American Journal of Medical Genetics. Part C, Seminars in Medical Genetics·Patrick Baud
Mar 28, 2006·Journal of Psychiatric Research·Maj Vinberg ChristensenLars Vedel Kessing
Feb 15, 2008·International Journal of Mental Health Systems·Graham W MellsopSelim M El-Badri
Jan 17, 2008·The Australian and New Zealand Journal of Psychiatry·Dannette Marie, Brad Miles
Apr 3, 2007·The British Journal of Psychiatry : the Journal of Mental Science·Vincent LorantMarc Ansseau
Apr 24, 2001·The British Journal of Psychiatry. Supplement·B Cooper
Feb 16, 2019·Perspectives in Psychiatric Care·Yadigar Çevik Durmaz, Gül Ünsal
Jun 25, 2002·The Journal of Nervous and Mental Disease·Gin S MalhiPhilip B Mitchell
Feb 3, 2005·The Journal of Nervous and Mental Disease·Russell NoyesBradley N Doebbeling
Apr 3, 2001·The British Journal of Psychiatry : the Journal of Mental Science·A T Cheng, B Cooper

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Psychiatry : the Journal of the Association of European Psychiatrists
Leda ChatziManolis Kogevinas
International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology
Stefan KoelschHolger Stepan
Twin Research : the Official Journal of the International Society for Twin Studies
David GaistJaakko Kaprio
© 2021 Meta ULC. All rights reserved