Abstract
Most published definitions of the metabolic syndrome (MetS) in children and adolescents include increased waist circumference (WC) in their criteria. To assess the clinical relevance of WC in identifying adolescents with the MetS phenotype and adverse fitness patterns, we divided a cohort of 15-year-old schoolchildren in quartiles for WC, and compared the subjects of the extreme quartiles for the presence of cardiovascular (CVD) risk factors, their clustering, insulin resistance and body fitness. From the original cohort of 635 adolescents investigated for childhood CVD risk, anthropometric parameters, blood pressure, fitness indexes, and serum fasting glucose, insulin and lipids were analyzed in 105 adolescents of the highest (> or =75th percentile) and 102 of the lowest (< or =25th percentile) WC quartile. Adolescents with WC > or =75th percentile presented with significantly higher fasting insulin (17+/-0.9 vs. 9.1+/-1.0 microIU/mL), triglycerides (78.0+/-3.4 vs. 62.3+/-3.3 mg/dL), LDL-cholesterol (106.8+/-2.8 vs. 96.1+/-2.8 mg/dL), homeostasis model assessment index (HOMA-IR) (3.29+/-1.8 vs. 1.81+/-0.2), systolic blood pressure (125.6+/-1.1 vs. 116.0+/-1.1 mm Hg), and diastolic blood pressure (78.0+/-0.9 vs. 71.5+/-0.9 mm H...Continue Reading
Citations
Aug 11, 2012·BMC Public Health·Reijo SirenHannu Vanhanen
Jan 2, 2013·Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy·Nasser M Rizk, Mervat Yousef
Apr 30, 2015·European Journal of Pediatrics·Ross H SandersStephen Cobley
Jun 14, 2016·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·D López-GonzálezN Garibay-Nieto
Jul 5, 2011·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·S P GarnettC T Cowell
Jul 18, 2015·International Journal of Environmental Research and Public Health·Rossana Gómez-CamposMarco Antonio Cossio-Bolaños
Aug 11, 2011·Pediatric Physical Therapy : the Official Publication of the Section on Pediatrics of the American Physical Therapy Association·Kathleen J GanleyMeghan Warren
Jan 16, 2013·International Journal of Obesity : Journal of the International Association for the Study of Obesity·T K HongM J Dibley
Apr 19, 2011·Annals of Human Biology·Raquel LeitãoGraça Simões Carvalho
Apr 3, 2012·Obesity Surgery·Milene A PufalCláudio C Mottin
Oct 16, 2012·European Journal of Pediatrics·Zhang Ying-XiuZhou Jing-Yang
Oct 9, 2012·Pediatric Obesity·M BarzinF Azizi
Dec 12, 2012·Journal of Clinical Nursing·María J AguilarJavier S Perona
Mar 24, 2018·Indian Journal of Pediatrics·Priscila Kurz de AssumpçãoMárcio Vinícius Fagundes Donadio
Jun 3, 2020·Pediatric Gastroenterology, Hepatology & Nutrition·Helen H WangDavid Q-H Wang
May 1, 2016·Revista paulista de pediatria : orgão oficial da Sociedade de Pediatria de São Paulo·Aline Dill WinckLetiane Bueno Zanatta
Dec 19, 2020·Acta Paediatrica·Lachlan MitchellCecily Kelleher
Oct 19, 2017·Nutrition Research·Javier S PeronaEmilio González-Jiménez
Jul 7, 2010·Pediatrics·Olubukola O NafiuKevin K Tremper