PMID: 2124005Aug 1, 1990Paper

Waldenstrom's macroglobulinemia presenting with pleuropulmonary and gastric manifestations

Singapore Medical Journal
J C Yap, S C Poh

Abstract

A case of Waldenstrom's macroglobulinemia is reported in which the main clinical presentation was related to pulmonary infiltrations and pleural effusion. Serum protein studies demonstrated the characteristic monoclonal increase in immunoglobulin M (IgMK). Pleural and percutaneous lung biopsies showed dense lymphocytic infiltration. Gastric biopsy also showed focal atypical lymphoid hyperplasia. There was good clinical and radiological response to treatment with chlorambucil and prednisolone.

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