Wall Shear Stress Estimation of Thoracic Aortic Aneurysm Using Computational Fluid Dynamics

Computational and Mathematical Methods in Medicine
J FebinaN M Sudharsan

Abstract

An attempt has been made to evaluate the effects of wall shear stress (WSS) on thoracic aortic aneurysm (TAA) using Computational Fluid Dynamics (CFD). Aneurysm is an excessive localized swelling of the arterial wall due to many physiological factors and it may rupture causing shock or sudden death. The existing imaging modalities such as MRI and CT assist in the visualization of anomalies in internal organs. However, the expected dynamic behaviour of arterial bulge under stressed condition can only be effectively evaluated through mathematical modelling. In this work, a 3D aneurysm model is reconstructed from the CT scan slices and eventually the model is imported to Star CCM+ (Siemens, USA) for intensive CFD analysis. The domain is discretized using polyhedral mesh with prism layers to capture the weakening boundary more accurately. When there is flow reversal in TAA as seen in the velocity vector plot, there is a chance of cell damage causing clots. This is because of the shear created in the system due to the flow pattern. It is observed from the proposed mathematical modelling that the deteriorating WSS is an indicator for possible rupture and its value oscillates over a cardiac cycle as well as over different stress condi...Continue Reading

References

Sep 1, 1994·Biorheology·P D BallykC R Ethier
Dec 21, 2005·Heart·Raimund Erbel, Holger Eggebrecht
Nov 4, 2006·Biomedical Engineering Online·Alessandro BorghiX Yun Xu
Dec 22, 2006·Annals of the New York Academy of Sciences·Ramon BerguerKhalil Khanafer
Nov 7, 2012·Journal of Vascular Surgery·Eric K ShangBenjamin M Jackson
Feb 24, 2015·Journal of Vascular Surgery·Lauren D C CasaDavid N Ku
Aug 4, 2015·Computer Methods in Biomechanics and Biomedical Engineering·F M CallaghanS M Grieve
Jan 23, 2016·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Satoshi NumataHitoshi Yaku
Jan 29, 2016·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Michael MarklAlex J Barker

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Citations

Jul 21, 2020·Evolutionary Anthropology·Stephanie A Poindexter, Eva C Garrett
Oct 18, 2020·Cardiovascular and Interventional Radiology·Götz M Richter
Mar 17, 2021·Nature Biomedical Engineering·Charlie DemenéFabienne Perren
Jun 19, 2021·Frontiers in Cardiovascular Medicine·Lauren JohnstonAsimina Kazakidi
Nov 11, 2021·Investigative Ophthalmology & Visual Science·Lan-Ting WuYan-Ling Wang

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Software Mentioned

MIMICS
Star CCM +

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