War gases as olfactory probes

Science
D W CriswellK R Brower

Abstract

The tear gas ethyl bromoacetate is a fruity-smelling alkylating agent that blocks the ability of the frog nose to respond to esters and a variety of other odorants, but leaves sensitivity to amines unimpaired. Lachrymators and chemical warfare agents of other functional types such as sulfides (mustard gas) and amines (nitrogen mustards) may have similarly specific actions that will enable their use as chemical probes of the sense of smell.

References

Jun 1, 1972·Proceedings of the National Academy of Sciences of the United States of America·M L Getchell, R C Gesteland
Apr 16, 1974·Life Sciences·A Karlin
Jun 4, 1971·Science·L Friedman, J G Miller
Sep 1, 1966·The Journal of Physiology·K B Döving
Jan 1, 1972·Methods in Enzymology·F R Gurd

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Citations

Jan 1, 1987·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·R SchaferS P Fracek
Mar 15, 1986·Experientia·S J Kleene
Apr 1, 1989·Journal of Clinical Pharmacology·Y RothY Glovinsky
Dec 1, 1989·The American Journal of Physiology·R R Anholt

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