Warfarin Safety: A Cross-Sectional Study of the Factors Associated with the Consumption of Medicinal Plants in a Brazilian Anticoagulation Clinic

American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions
Paula Mendonça LeiteRachel Oliveira Castilho

Abstract

The aim of this study was to analyze factors associated with the consumption of medicinal plants by patients being treated with warfarin in a Brazilian anticoagulation clinic and to study the safety of medicinal plant use in patients on warfarin therapy. The study was performed as an observational cross-sectional analysis. Study participants were outpatients on long-term warfarin therapy for at least 2 months for atrial fibrillation or prosthetic cardiac valves. Interviews were carried out concerning information about the habits of medicinal herb consumption, and logistic regression analysis was performed to identify factors associated with the consumption of herbs. The scientific names of the medicinal plants were identified to search for information on the effects on the hemostasis of the interactions between the medicinal herbs reported and warfarin. The mean age of the 273 patients included was 60.8 years; 58.7% were women. Medicinal plants were used by 67% of the participants. No association between demographic and clinical data and the use of medicinal plants was identified. Patients reported a total of 64 different plants, primarily consumed in the form of tea. The plants were mainly used to treat respiratory tract and c...Continue Reading

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Citations

Oct 24, 2019·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Paula M LeiteRachel O Castilho
Dec 10, 2019·Journal of Cardiovascular Pharmacology·Paula Mendonça LeiteRachel Oliveira Castilho
Sep 12, 2018·Diseases·Brandon J PerumpailAijaz Ahmed
Jul 18, 2021·Journal of Basic and Clinical Physiology and Pharmacology·Paula Mendonça LeiteRachel Castilho
Sep 3, 2021·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Paula Mendonça LeiteRachel Oliveira Castilho

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