Wash-in and wash-out of sevoflurane in a test-lung model: A comparison between Aisys and FLOW-i

F1000Research
Petter JakobssonJ Jakobsson

Abstract

Background: Modern anaesthesia workstations are reassuringly tight and are equipped with effective gas monitoring, thus providing good opportunities for low/minimal flow anaesthesia. A prerequisite for effective low flow anaesthesia is the possibility to rapidly increase and decrease gas concentrations in the circle system, thereby controlling the depth of anaesthesia.  Methods: We studied the wash-in and wash-out of sevoflurane in the circle system with fixed fresh gas flow and vaporizer setting. We compared two modern anaesthesia work stations, the Aisys (GE, Madison, WI, USA) and FLOW-i (Maquet, Solna, Sweden) in a test lung model.  Results: We found fresh-gas flow to have, as expected, a major influence on wash-in, as well as wash-out of sevoflurane. The wash-in time to reach a stable circle 1 MAC (2.1%) decreased from an average of 547 ± 83 seconds with a constant fresh gas flow of 300 ml/min and vaporizer setting of 8%, to a mean of 38 ± 6 seconds at a fresh gas flow of 4 L/min. There were only minor differences between the two works-stations tested; the Aisys was slightly faster at both 300 and 4 L/min flow. Time to further increase circle end-tidal concentration from 1-1.5 MAC showed likewise significant associations to...Continue Reading

References

Aug 1, 1994·Anaesthesia and Intensive Care·P P Kleemann
Mar 15, 2012·Anesthesia and Analgesia·Jeffrey M Feldman
Jun 2, 2012·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Metha BrattwallJan Jakobsson
Jun 15, 2015·Journal of Clinical Monitoring and Computing·Rik CaretteJan F A Hendrickx
Apr 12, 2016·Journal of Clinical Monitoring and Computing·Umberto LucangeloWalter A Zin

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