Water and bovine serum lubrication compared in simulator PTFE/CoCr wear model

Journal of Biomedical Materials Research
V GoodL Anissian

Abstract

Controversy surrounds wear data from laboratory hip simulator studies, whether derived from water-based or serum-based studies or whether a major design parameter such as the size of the femoral head has an effect on the volume of wear particulate released. To investigate these relationships, we studied cup wear in water- and serum-based lubricants using as our standard the polytetrafluoroethylene (PTFE) data derived by Charnley. To model Charnley's clinical experience, PTFE acetabular cups were used in sets of three each of four sizes of CoCr femoral heads: 22.25-, 28-, 32-, and 42-mm diameters. Six criteria were used to evaluate the performance of the lubricants against clinical accuracy and scientific methods. The PTFE wear data from the serum-based tests was consistently linear with the duration of the test, exhibited a precision within +/-3% about the average for each set of three cups, and copious amounts of wear debris were clearly seen circulating and settling to the bottom of the wear chambers. The wear data clearly demonstrated Charnley's thesis that volume of wear increases with regard to the size of the femoral head in a linear manner. This increase was considered satisfactory at 9%/ mm. However, in terms of clinica...Continue Reading

Citations

Dec 18, 2001·Journal of Biomedical Materials Research·H L AnissianI C Clarke
Jun 29, 2010·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Victoria K MaskiewiczIan C Clarke
Dec 30, 2011·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·A P Harsha, T J Joyce
Sep 28, 2000·Journal of Biomedical Materials Research·S M KurtzA A Edidin
Oct 20, 2000·Clinical Orthopaedics and Related Research·I C Clarke, A Gustafson
Dec 9, 2003·Journal of Biomedical Materials Research. Part a·Hironobu OonishiShingo Masuda
May 11, 2016·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Simon L SmithThomas J Joyce
Mar 23, 2000·Journal of Dental Research·J P van LoonL G de Bont
Jan 15, 2000·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·S L SmithA Unsworth
Sep 21, 2000·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·I C ClarkeG Gustafson
Dec 23, 2003·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·A WangG Schmidig
Nov 14, 2000·Journal of Biomedical Materials Research·S L SmithA Unsworth
Nov 30, 2005·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·T SchwenkeUNKNOWN International Standards Organization

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.