Water as a Hydrogenating Agent: Stereodivergent Pd-Catalyzed Semihydrogenation of Alkynes

Organic Letters
Chuan-Qi ZhaoTian-Sheng Mei

Abstract

Palladium-catalyzed transfer semihydrogenation of alkynes using H2O as the hydrogen source and Mn as the reducing reagent is developed, affording cis- and trans-alkenes selectively under mild conditions. In addition, this method provides an efficient way to access various cis-1,2-dideuterioalkenes and trans-1,2-dideuterioalkenes by using D2O instead of H2O.

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Citations

Apr 30, 2019·Chemical Communications : Chem Comm·Kangkui LiBaomin Fan
May 30, 2019·Chemical Communications : Chem Comm·Xiaowei HanZhuangzhi Shi

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