PMID: 6990797May 1, 1980Paper

Water flux in animals: analysis of potential errors in the tritiated water method

The American Journal of Physiology
K A Nagy, D P Costa

Abstract

Laboratory studies indicate that tritiated water measurements of water flux are accurate to within -7 to +4% in mammals, but errors are larger in some reptiles. However, under conditions that can occur in field studies, errors may be much greater. Influx of environmental water vapor via lungs and skin can cause errors exceeding +/- 50% in some circumstances. If water flux rates in an animal vary through time, errors approach +/- 15% in extreme situations, but are near +/- 3% in more typical circumstances. Errors due to fractional evaporation of tritiated water may approach -9%. This error probably varies between species. Use of an inappropriate equation for calculating water flux from isotope data can cause errors exceeding +/- 100%. The following sources of error are either negligible or avoidable: use of isotope dilution space as a measure of body water volume, loss of nonaqueous tritium bound to excreta, binding of tritium with nonaqueous substances in the body, radiation toxicity effects, and small analytical errors in isotope measurements. Water flux rates measured with tritiated water may be expected to be within +/- 10% of actual flux rates in most situations.

Citations

Sep 25, 2009·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Delphine VerrierJohn P Y Arnould
Jun 27, 2018·The Journal of Experimental Biology·James K Kagya-AgyemangJohn R Speakman
Jun 19, 2002·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Robert L Nudds, David M Bryant
Nov 6, 2003·American Journal of Physiology. Renal Physiology·Aarthi RamanFrances A Tylavsky
Nov 16, 2002·Journal of Applied Physiology·R Van TrigtG H Visser
May 22, 2003·American Journal of Physiology. Endocrinology and Metabolism·Robert Brommage
Nov 11, 2016·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Pauke C SchotsErling S Nordøy
Oct 26, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·G H VisserT Piersma
Mar 11, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·M ScantleburyJ R Speakman
Jan 9, 2003·The Journal of Experimental Biology·Todd J McWhorterBerry Pinshow
May 29, 2003·The Journal of Experimental Biology·Peter J Hodum, Wesley W Weathers
Oct 29, 2003·The Journal of Experimental Biology·E Król, J R Speakman
Aug 27, 2003·The Journal of Experimental Biology·Martin BiuwMike Fedak

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The American Journal of Clinical Nutrition
D A SchoellerP D Klein
Clinical Physics and Physiological Measurement : an Official Journal of the Hospital Physicists' Association, Deutsche Gesellschaft Für Medizinische Physik and the European Federation of Organisations for Medical Physics
T SmithR Hesp
Journal of Applied Physiology: Respiratory, Environmental and Exercise Physiology
E W ColtR N Pierson
© 2021 Meta ULC. All rights reserved