Water protective effect of barrier creams and moisturizing creams: a new in vivo test method

Contact Dermatitis
F de Fine OlivariusH C Wulf

Abstract

Frequent exposure to water is an important risk factor for the development of irritant hand eczema. Evaluation of cream efficacy in protecting against water is difficult. A new non-irritant, non-invasive method is introduced, based on evaluation of colour intensities when an aqueous solution of crystal violet is applied to the skin, after pretreatment with different creams. By skin reflectance measurement, differences in colour intensity were objectified. Measurements of transepidermal water loss were also performed, 2 barrier creams and a moisturizer were tested on the dorsal and volar aspects of the hands. One barrier cream contained silicone, the other solid particles. The moisturizer had a high content of lipid. In one experiment, the immediate effect of the creams in protecting against water was evaluated. In a second experiment, the water resistancy of the creams was tested, using a standardized water immersion procedure (4 x 20 min). The barrier cream with particles gave the best immediate protection (dorsal 76%, volar 69%). The moisturizer was intermediately protective (dorsal 57%, volar 34%), while very little protection was found for the silicone-containing cream (dorsal 16%, volar 10%). The water immersion procedure ...Continue Reading

References

Feb 1, 1996·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·S SeidenariG Pellacani

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Citations

Aug 13, 2011·Archives of Dermatological Research·Dimitrios PapakostasAnnika Vogt
Sep 6, 2001·Clinics in Dermatology·T C FlynnG E Viehman
Oct 19, 1999·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·E Larson
Apr 20, 1999·Contact Dermatitis·T Shimizu, H I Maibach
May 1, 1998·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·G B Jemec, H C Wulf
Mar 15, 2014·Anais Brasileiros De Dermatologia·João Roberto AntonioJoão Rodrigo Oliveira
Jul 8, 2009·Dermatologic Clinics·Shane C Clark, Matthew J Zirwas
Nov 22, 2005·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Peter J FroschBeate Grunenberg
Jun 20, 2007·Contact Dermatitis·Tina RiegerJürgen Lademann
Jan 21, 2009·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Catarina RosadoLuis Monteiro Rodrigues
May 5, 2012·International Journal of Cosmetic Science·N DomotoT Tsuji
Jan 22, 2013·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Johan du PlessisLinn Holness
Apr 10, 2003·International Archives of Occupational and Environmental Health·Birgitta Kütting, Hans Drexler

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