Water-soluble Py-BIPS spiropyrans as photoswitches for biological applications

Organic Letters
Cem ÖzçobanAlexander Heckel

Abstract

The ultrafast photochemistry of a new spiropyran photoswitch (Py-BIPS) has been investigated, revealing many advantages in the application in water over the previously studied spiropyrans. Functionalized Py-BIPS derivatives are presented for the study of pH dependence, stability, toxicity, and the thermal and photochemical behavior on longer time scales in aqueous media using several spectroscopic methods. These investigations pave the way for the practical use of Py-BIPS derivatives as photoswitchable ligands of biomolecules.

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Citations

Dec 25, 2015·Journal of the American Chemical Society·Derk Jan van DijkenBen L Feringa
Mar 24, 2016·The Journal of Physical Chemistry Letters·Tim Stauch, Andreas Dreuw
Jul 28, 2016·Organic Letters·Yaoyao XiongHarry L Anderson
Oct 22, 2016·Chemical Reviews·Tim Stauch, Andreas Dreuw
Mar 30, 2016·Physical Chemistry Chemical Physics : PCCP·C SlavovM Braun
Jul 6, 2017·The Journal of Organic Chemistry·Bijnaneswar MondalPartha Sarathi Mukherjee
Jul 8, 2017·The Journal of Organic Chemistry·Thomas HalbritterAlexander Heckel
May 28, 2016·Physical Chemistry Chemical Physics : PCCP·Tim Stauch, Andreas Dreuw
Nov 8, 2016·Physical Chemistry Chemical Physics : PCCP·David Mendive-TapiaDenis Jacquemin
Oct 23, 2015·Chemistry : a European Journal·Thomas GoldauAlexander Heckel
Jun 25, 2016·Beilstein Journal of Organic Chemistry·Christopher SarterAndres Jäschke

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