PMID: 6402916Mar 1, 1983Paper

Water soluble vitamin requirements in home parenteral nutrition patients

The American Journal of Clinical Nutrition
L HowardC Tenny

Abstract

Ascorbic acid, thiamin, niacin, pyridoxine, and folic acid status was evaluated in eight physiologically stable home parenteral nutrition patients. Six of these subjects received these vitamins as a twice weekly bolus and were studied over a period of 6 days. All vitamin levels were normal except for blood thiamin which was low, 72 h after each bolus. Since transketolase levels remained normal, this fall in blood thiamin probably had no functional significance. The urine excretion pattern of niacin and pyridoxine indicated normal metabolism and retention of these vitamins. Two patients, who required only parenteral fluid and electrolytes to remain weight stable, received none of these vitamins parenterally, but also maintained adequate vitamin status. These results suggest that in long term home parenteral nutrition patients these five vitamins can safely be given twice weekly, rather than daily, and that short bowel patients who maintain their weight without intravenous calories and protein also assimilate adequate amounts of these proximally absorbed water soluble vitamins from their diet.

Citations

Jun 1, 1984·Journal of Clinical and Hospital Pharmacy·M C Allwood
Sep 1, 1984·Journal of Clinical and Hospital Pharmacy·M C Allwood
May 1, 1987·JPEN. Journal of Parenteral and Enteral Nutrition·L Howard
Mar 1, 1988·JPEN. Journal of Parenteral and Enteral Nutrition·D LabadariosG S Shephard
Oct 19, 2001·Journal of Clinical Gastroenterology·V MikalunasR M Craig
Jun 27, 2015·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Vincent W VanekUNKNOWN Novel Nutrient Task Force Parenteral Vitamin and Trace Element Working Group and the American Society for Parenteral and Ent

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