Water uptake and release from iodine-containing bone cement

Journal of Biomedical Materials Research. Part a
F KjellsonL Lidgren

Abstract

Water uptake and release characteristics of PMMA cement containing the water-soluble contrast media iohexol or iodixanol have been investigated. The water uptake study revealed that iohexol had the highest uptake of water (3.7%) and that iodixanol had an uptake close to that of Palacos R (2.3% and 1.9%). The curves obtained showed the materials to follow classic diffusion theory, with an initial linearity with respect to t(1/2) making it possible to calculate the diffusion coefficients. This showed iohexol to have the lowest diffusion coefficient, Palacos R the highest, and iodixanol close to that of Palacos R. The release study showed that more iohexol than iodixanol was released from the bone cement; the long-term release was above 25 microg/mL for iohexol compared to slightly above 10 microg/mL for iodixanol. A microCT investigation showed that the risk of developing an observable radiolucent zone is negligible.

References

Jan 1, 1990·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·L CaraviaB Jobbins
Jan 1, 1986·The Journal of Arthroplasty·W L BargarM T Madison
Jan 1, 1997·The Journal of Bone and Joint Surgery. British Volume·A SabokbarN A Athanasou
Apr 4, 2001·The Journal of Bone and Joint Surgery. British Volume·J A WimhurstN Rushton
Apr 9, 2001·International Journal of Pharmaceutics·S TorradoG Frutos
Feb 13, 2003·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·M BaleaniA Toni
Jul 21, 2004·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·F KjellsonL Lidgren
Sep 7, 2004·Journal of Materials Science. Materials in Medicine·M P PatelM Braden
Sep 7, 2004·Journal of Materials Science. Materials in Medicine·F KjellsonL Lidgren
Sep 7, 2004·Journal of Materials Science. Materials in Medicine·R De SantisD Ronca

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Citations

Feb 1, 2007·Journal of Materials Science. Materials in Medicine·Fred KjellsonLars Lidgren
Jan 22, 2011·The Knee·Stephen H WhitePeter W Jones
Jun 26, 2007·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Gladius Lewis
Nov 30, 2006·Journal of Biomedical Materials Research. Part a·Gladius LewisJulio San Román
Apr 7, 2007·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Markus NottrottNils Roar Gjerdet
May 28, 2010·Acta Orthopaedica. Supplementum·Markus Nottrott

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