WBC Associates with Readmission Following Cystectomy

Bladder Cancer
Andrew G McIntoshPhilip H Abbosh

Abstract

Background: Radical cystectomy is associated with perioperative complication rates exceeding 50% in some series. Readmission rates are increasingly used as a surgical quality metric. White blood cell count is a crude surrogate for physiologic processes which may reflect postoperative complications leading to readmission. Objective: We assessed the association between final white blood cell count at discharge and risk of readmission following radical cystectomy. Methods: Records on 477 patients undergoing radical cystectomy from 2006-2013 were reviewed. Final white blood cell count was defined as the last documented value during index admission. Univariate analysis was performed using Fisher's exact, Wilcoxon rank sum test, and Spearman's coefficient tests where appropriate. Multivariable logistic regression models were used to test the associations between final white blood cell count and readmission. Results: 34% of patients were readmitted within 90 days of surgery. Amongst this cohort, a cutoff final white blood cell count of 9000/mm(3) was identified, with a significantly higher proportion of patients with values >9000/mm(3) experiencing readmission than those with values≤9000/mm(3) (42% vs 28%, p = 0.004). Other perioperat...Continue Reading

References

Sep 10, 2003·The Annals of Thoracic Surgery·Lawrence J DaceyGerald T O'Connor
Sep 8, 2005·The Journal of Urology·Brent K HollenbeckJohn T Wei
Dec 13, 2006·The Journal of Urology·Badrinath R Konety, Veerasathpurush Allareddy
Apr 14, 2009·Journal of Cardiothoracic and Vascular Anesthesia·Manuel L FontesHoward Thaler
Jul 21, 2009·The Journal of Urology·Giacomo NovaraVincenzo Ficarra
Jul 21, 2010·The Journal of Urology·Richard E HautmannBjoern G Volkmer
Nov 3, 2011·Nature Reviews. Urology·Richard E HautmannOliver Hautmann
Aug 25, 2012·European Urology·Georgios GakisUNKNOWN International Consultation on Urologic Disease-European Association of Urology Consultation on Bladder Cancer 2012
May 16, 2013·American Journal of Hematology·Carmen VenetzDrahomir Aujesky
Aug 3, 2013·International Journal of Urology : Official Journal of the Japanese Urological Association·Florian RoghmannJüri Palisaar
Aug 3, 2013·Current Opinion in Urology·Kyle A Richards, Gary D Steinberg
Jan 15, 2014·International Journal of Radiation Oncology, Biology, Physics·Chad TangZhongxing Liao
Feb 13, 2014·The Journal of Urology·Siamak DaneshmandHooman Djaladat
Apr 20, 2014·Journal of Endourology·Stavros SfoungaristosMordechai Duvdevani
Nov 20, 2014·Canadian Urological Association Journal = Journal De L'Association Des Urologues Du Canada·Giorgio GandagliaQuoc-Dien Trinh
Dec 3, 2014·The Journal of Urology·Ted A SkolarusBrent K Hollenbeck

❮ Previous
Next ❯

Methods Mentioned

BETA
coronary artery bypass

Software Mentioned

SAS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.