PMID: 5902395Jan 28, 1966

Weaning of young rats: effect of time on behavior

Science
V NOVAKOVA

Abstract

Male rats were weaned on the 15th, 16th, 17th, 25th, and 30th day of postnatal life. The rate of elaboration of the conditioned reflex at 8 months of age and the stability of the memory trace at 12 months were studied. Compared with rats weaned at 30 days of age, those weaned on day 15 elaborated the conditioned reflex much more slowly and the memory trace was less firm. Rats weaned on days 16 and 17 elaborated the conditioned reflex more quickly than rats weaned on day 15 but more slowly than those weaned on day 30. In all groups the memory trace showed the same stability and was significantly firmer than in rats weaned on day 15. The higher nervous activity of rats weaned at the age of 25 days more nearly resembles that of rats weaned at 15 days than the 30th day.

Citations

May 8, 1979·Psychopharmacology·H L RüthrichH Matthies
May 1, 1973·The American Journal of Cardiology·W K Schubert
Jan 1, 1972·Physiology & Behavior·S M Plaut, J M Davis
Sep 1, 1976·Physiology & Behavior·J M De Castro, S Balagura
May 1, 1999·Physiology & Behavior·A LorancaM Salas
Nov 16, 2006·Annals of the New York Academy of Sciences·Libor Velísek
Apr 1, 1975·Behavioral Biology·D I WilliamsM H Lee

Related Concepts

Senility
Behavior, Animal
Conditioning (Psychology)
Conditioned Reflex
Memory
Weaning

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Genetic Screens in iPSC-derived Brain Cells

Genetic screening is a critical tool that can be employed to define and understand gene function and interaction. This feed focuses on genetic screens conducted using induced pluripotent stem cell (iPSC)-derived brain cells. It also follows CRISPR-Cas9 approaches to generating genetic mutants as a means of understanding the effect of genetics on phenotype.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Pediculosis pubis

Pediculosis pubis is a disease caused by a parasitic insect known as Pthirus pubis, which infests human pubic hair, as well as other areas with hair including eye lashes. Here is the latest research.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Rh Isoimmunization

Rh isoimmunization is a potentially preventable condition that occasionally is associated with significant perinatal morbidity or mortality. Discover the latest research on Rh Isoimmunization here.

Pharmacology of Proteinopathies

This feed focuses on the pharmacology of proteinopathies - diseases in which proteins abnormally aggregate (i.e. Alzheimer’s, Parkinson’s, etc.). Discover the latest research in this field with this feed.

Enzyme Evolution

This feed focuses on molecular models of enzyme evolution and new approaches (such as adaptive laboratory evolution) to metabolic engineering of microorganisms. Here is the latest research.

Alignment-free Sequence Analysis Tools

Alignment-free sequence analyses have been applied to problems ranging from whole-genome phylogeny to the classification of protein families, identification of horizontally transferred genes, and detection of recombined sequences. Here is the latest research.