Wear resistance of the biocompatible phospholipid polymer-grafted highly cross-linked polyethylene liner against larger femoral head

Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society
Toru MoroSakae Tanaka

Abstract

The use of larger femoral heads to prevent the dislocation of artificial hip joints has recently become more common. However, concerns about the subsequent use of thinner polyethylene liners and their effects on wear rate have arisen. Previously, we prepared and evaluated the biological and mechanical effects of a novel highly cross-linked polyethylene (CLPE) liner with a nanometer-scaled graft layer of poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC). Our findings showed that the PMPC-grafted particles were biologically inert and caused no subsequent bone resorptive responses and that the PMPC-grafting markedly decreased wear in a hip joint simulator. However, the metal or ceramic femoral heads used in this previous study had a diameter of 26 mm. Here, we investigated the wear-resistance of the PMPC-grafted CLPE liner with a 40-mm femoral head during 10 × 10(6) cycles of loading in the hip joint simulator. The results provide preliminary evidence that the grafting markedly decreased gravimetric wear rate and the volume of wear particles, even when coupled with larger femoral heads. Thus, we believe the PMPC-grafting will prolong artificial hip joint longevity both by preventing aseptic loosening and by improving the stabi...Continue Reading

References

Jan 1, 1996·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·P CampbellH C Amstutz
Jan 26, 1999·Clinical Orthopaedics and Related Research·L D Dorr, Z Wan
Feb 11, 1999·The Journal of Bone and Joint Surgery. American Volume·T P Schmalzried, J J Callaghan
Jan 21, 2003·The Journal of Bone and Joint Surgery. American Volume·Charlotte B PhillipsJeffrey N Katz
Dec 4, 2004·Clinical Orthopaedics and Related Research·William H Harris
Oct 4, 2006·Clinical Orthopaedics and Related Research·John H DumbletonAiguo Wang
Oct 21, 2006·Clinical Orthopaedics and Related Research·Toru MoroHiroshi Kawaguchi
Oct 3, 2007·The Journal of Bone and Joint Surgery. American Volume·Stephen S TowerMichael B Mayor
May 3, 2008·The Journal of Bone and Joint Surgery. British Volume·S Glyn-JonesD W Murray
Oct 24, 2008·The Journal of Arthroplasty·C Van SikesThorsten M Seyler
Jan 6, 2009·The Journal of Bone and Joint Surgery. American Volume·Kevin J BozicDaniel J Berry
Aug 20, 2009·Clinical Orthopaedics and Related Research·Paul F LachiewiczJohn M Martell
Sep 25, 2009·The Journal of Arthroplasty·Eric Mark HammerbergLawrence D Dorr
Nov 10, 2009·Clinical Orthopaedics and Related Research·Natalie H KellyGeoffrey H Westrich
Sep 17, 2010·Clinical Orthopaedics and Related Research·William N CapelloMarybeth Naughton
Sep 18, 2010·Clinical Orthopaedics and Related Research·Fu-Wen ShenHarry A McKellop
Oct 19, 2010·Clinical Orthopaedics and Related Research·Adolph V LombardiOrlando J Franchi
Dec 7, 2010·Clinical Orthopaedics and Related Research·Masayuki KyomotoKazuhiko Ishihara
Jun 22, 2012·The Journal of Bone and Joint Surgery. American Volume·Donald W HowieUNKNOWN Large Articulation Study Group
Nov 9, 2012·The Journal of Bone and Joint Surgery. British Volume·J A Rodriguez, P A Rathod
Jul 19, 2013·Clinical Orthopaedics and Related Research·Aaron J JohnsonMichael A Mont
Nov 6, 2013·The Bone & Joint Journal·P J Brooks
Nov 20, 2013·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Toru MoroHiroshi Kawaguchi

❮ Previous
Next ❯

Citations

Nov 5, 2016·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Toru MoroKozo Nakamura
Mar 7, 2017·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Kenichi WatanabeKazuhiko Ishihara
May 10, 2017·Materials Science & Engineering. C, Materials for Biological Applications·Qi LiXiaohao Wang
Sep 25, 2017·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Kevin J WarburtonTrevor J Lujan
Feb 16, 2019·Materials·Massimiliano Merola, Saverio Affatato
Feb 24, 2017·Science and Technology of Advanced Materials·Subir Ghosh, Sylvester Abanteriba
May 14, 2021·JBJS Reviews·Amit ParekhMark Gonzalez

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.