Web-based intervention to improve quality of life in late stage bipolar disorder (ORBIT): randomised controlled trial protocol

BMC Psychiatry
Kathryn FletcherGreg Murray

Abstract

The primary objective of this randomised controlled trial (RCT) is to establish the effectiveness of a novel online quality of life (QoL) intervention tailored for people with late stage (≥ 10 episodes) bipolar disorder (BD) compared with psychoeducation. Relative to early stage individuals, this late stage group may not benefit as much from existing psychosocial treatments. The intervention is a guided self-help, mindfulness based intervention (MBI) developed in consultation with consumers, designed specifically for web-based delivery, with email coaching support. This international RCT will involve a comparison of the effectiveness and cost-effectiveness of two 5-week adjunctive online self-management interventions: Mindfulness for Bipolar 2.0 and an active control (Psychoeducation for Bipolar). A total of 300 participants will be recruited primarily via social media channels. Main inclusion criteria are: a diagnosis of BD (confirmed via a phone-administered structured diagnostic interview), no current mood episode, history of 10 or more mood episodes, no current psychotic features or active suicidality, under the care of a medical practitioner. Block randomisation will be used for allocation to the interventions, and partici...Continue Reading

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Citations

Aug 14, 2020·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Martin D ProvencherErin E Michalak
Sep 11, 2020·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Greg MurrayHolly A Swartz
Dec 24, 2020·The Australian and New Zealand Journal of Psychiatry·Gin S MalhiGreg Murray

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Methods Mentioned

BETA
pharmacotherapy
Cognitive Behavioural Therapy

Clinical Trials Mentioned

NCT03197974

Software Mentioned

SAS
Qualtrics
ORBIT Online Individualised Tool
ORBIT

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