PMID: 2110969Apr 1, 1990Paper

Weber and noise adaptation in the retina of the toad Bufo marinus

The Journal of General Physiology
K DonnerT Reuter

Abstract

Responses to flashes and steps of light were recorded intracellularly from rods and horizontal cells, and extracellularly from ganglion cells, in toad eyecups which were either dark adapted or exposed to various levels of background light. The average background intensities needed to depress the dark-adapted flash sensitivity by half in the three cell types, determined under identical conditions, were 0.9 Rh*s-1 (rods), 0.8 Rh*s-1 (horizontal cells), and 0.17 Rh*s-1 (ganglion cells), where Rh* denotes one isomerization per rod. Thus, there is a range (approximately 0.7 log units) of weak backgrounds where the sensitivity (response amplitude/Rh*) of rods is not significantly affected, but where that of ganglion cells (1/threshold) is substantially reduced, which implies that the gain of the transmission from rods to the ganglion cell output is decreased. In this range, the ganglion cell threshold rises approximately as the square root of background intensity (i.e. in proportion to the quantal noise from the background), while the maintained rate of discharge stays constant. The threshold response of the cell will then signal light deviations (from a mean level) of constant statistical significance. We propose that this type of g...Continue Reading

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Citations

Jan 13, 2006·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Mimi M Ghim, William Hodos
Aug 1, 1991·Current Opinion in Neurobiology·D R Copenhagen
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May 24, 2016·Vision Research·Alejandro H GlorianiJuan A Aparicio
Jan 15, 2013·Progress in Retinal and Eye Research·Béla VölgyiRóbert Gábriel
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Sep 4, 2021·Proceedings of the National Academy of Sciences of the United States of America·Jerome CarriotMaurice J Chacron

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