Apr 17, 2020

Toward a single dose cure for Buruli ulcer

BioRxiv : the Preprint Server for Biology
S. ThomasKevin Pethe

Abstract

A single dose of TELACEBEC (Q203), a phase 2 clinical candidate for tuberculosis, eradicates Mycobacterium ulcerans in a mouse model of Buruli ulcer infection without relapse up to 19 weeks post treatment. Clinical use of Q203 could dramatically simplify the clinical management of Buruli ulcer, a neglected mycobacterial disease.

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Mentioned in this Paper

Microorganism
Metabolic Process, Cellular
Russula archaea
Prokaryotic potassium channel
Classification
Genome
Archaea
Genomics
EAF2
Prokaryote

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