Weekly Changes in Axial Length and Choroidal Thickness in Children During and Following Orthokeratology Treatment With Different Compression Factors

Translational Vision Science & Technology
Jason K LauPauline Cho

Abstract

To determine the influence of compression factor upon changes in axial length and choroidal thickness during and following orthokeratology treatment. Orthokeratology lenses of different compression factors (one eye with 0.75 D and the fellow eye with 1.75 D) were randomly assigned to 28 subjects (median [range] age: 9.3 [7.8-11.0] years). Ocular biometrics were measured weekly for 1 month of lens wear and after lens cessation until the refraction stabilized (mean duration: 2.8 ± 0.4 weeks). Changes between eyes, and the associations between axial shortening and choroidal thickening with other ocular biometrics were analyzed. There were no significant between-eye differences in the changes of ocular biometrics (all P > 0.05). After adjusting for paired-eye data, axial length initially decreased by 26 ± 41 μm (P = 0.03) at week 1, then gradually returned to its original length. An approximate antiphase relationship of choroidal thickness (mean change: 9 ± 12 μm, P < 0.001) with axial length was observed. A significant rebound in axial length, but not choroidal thickness, occurred during the cessation period. Central corneal thinning and choroidal thickening accounted for 70% of initial axial shortening. Increasing the compression...Continue Reading

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Citations

Apr 28, 2020·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Mark A Bullimore, Kathryn Richdale
Apr 26, 2020·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Mark A Bullimore, Leah A Johnson
Mar 30, 2021·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Stephen J VincentLyndon Jones
May 12, 2021·Eye & Contact Lens·Yuanhao HeStephen J Vincent
Jul 26, 2021·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Biyue GuoPauline Cho

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