PMID: 11910598Mar 26, 2002Paper

Weight gain and the menopause: a 5-year prospective study

Climacteric : the Journal of the International Menopause Society
J R GuthrieE C Dudley

Abstract

To investigate prospectively changes in weight, skin-fold measurements, waist circumference and waist/hip ratio in relation to changes in menopausal status, hormone therapy use and life-style factors. The study was a 5-year follow-up of volunteers from a population-based cohort of Australian-born women aged 46-57 years at baseline: 106 premenopausal, 106 perimenopausal and 21 hormone therapy users. Mean (SD) weight gain of the entire cohort over 5 years was 2.1 (5.1) kg. Baseline age was negatively associated with weight change (regression coefficient = -0.4, SE 0.1, p < 0.05). After 5 years, 20 women remained premenopausal, 80 were perimenopausal, 112 had become naturally postmenopausal and 21 remained on hormone therapy. Changes in weight were greater than zero (p < 0.05) in all groups except for the women who remained on hormone therapy. There was no significant difference in weight gain between women who remained premenopausal and those who had a natural menopause. Increases in suprailiac skin-fold measurements (p < 0.05) and in waist circumference and waist/hip ratio occurred in women who experienced the menopausal transition but not in those who took hormone therapy continuously. There was no association between weight ch...Continue Reading

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