Weight gain during adjuvant and neoadjuvant chemotherapy for breast cancer: an audit of 100 women receiving FEC or CMF chemotherapy

Clinical Oncology : a Journal of the Royal College of Radiologists
K J LankesterP A Lawton

Abstract

Weight gain is reported as a common finding in patients treated for breast cancer but its aetiology appears to be complex. The aim of this study was to investigate the incidence and degree of weight gain during chemotherapy and to examine possible contributory factors. Data were collected on 100 women treated with CMF or FEC chemotherapy. The mean change in weight was +3.68 kg (P<0.001). 64% of patients gained more than 2 kg in weight, 31% maintained a stable weight (within + or - 2 kg) and 5 patients lost more than 2 kg. Approximately 1/3 of patients (33) gained more than 5 kg and 6 patients gained more than 10 kg in weight. The majority of patients (85%) received steroids as antiemetics but no effect of steroid dose was seen on the level of weight change. No significant differences in weight gain were seen in patients receiving tamoxifen (37%) compared with those not taking it. Similarly, menopausal status did not appear to be a significant factor influencing weight gain. In summary, a high incidence of weight gain was found. The literature on weight gain in breast cancer and possible interventions to avoid weight gain are discussed.

Citations

Jan 10, 2004·Integrative Cancer Therapies·D Barry Boyd
Sep 21, 2004·Oncology Nursing Forum·Vriginia W Hartmuller, Sharon M Desmond
Feb 2, 2017·Canadian Journal of Dietetic Practice and Research : a Publication of Dietitians of Canada = Revue Canadienne De La Pratique Et De La Recherche En Diététique : Une Publication Des Diététistes Du Canada·Vivienne VanceRhona Hanning
Apr 14, 2017·BMC Cancer·M M G A van den BergE Kampman
Apr 28, 2007·The Breast Journal·Grace Makari-JudsonWilson C Mertens
Apr 20, 2007·Clinical Journal of Oncology Nursing·Michelle Rooney, Adrienne Wald
Mar 28, 2008·Breast Cancer Research and Treatment·Hye-Suk HanJong Seok Lee
Aug 8, 2012·Breast Cancer Research and Treatment·A VillariniF Berrino
Dec 3, 2016·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Andrew G RenehanAnthony Howell
Dec 17, 2008·Current Oncology Reports·Dawn L HershmanKatherine D Crew
Mar 17, 2006·Breast Cancer Research and Treatment·Bette J CaanJohn P Pierce
Jun 24, 2008·Psychology, Health & Medicine·Rebecca L HelmsMarlaena Corso
Aug 8, 2013·British Journal of Cancer·S M ReddyV G Kaklamani
Apr 3, 2015·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Jamie S MyersJennifer Klemp
Mar 2, 2017·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Jamie S MyersCatherine M Bender
Oct 1, 2010·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·V VanceR Hanning
Dec 3, 2011·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·E GadéaX Durando
Mar 22, 2014·Molecular and Clinical Oncology·Jian-Sheng WangMing-Xin Zhang
Jun 5, 2018·The Proceedings of the Nutrition Society·A HeetunE R Copson
Feb 28, 2021·Health Promotion Journal of Australia : Official Journal of Australian Association of Health Promotion Professionals·Kate L PumpaDesmond Yip

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.