Weight maintenance following the STRIDE lifestyle intervention for individuals taking antipsychotic medications

Obesity
Carla A GreenVictor J Stevens

Abstract

Individuals taking antipsychotic medications have increased risk of obesity-related early morbidity/mortality. This report presents weight maintenance results from a successful weight loss and behavioral lifestyle change program developed for people taking antipsychotic medications. STRIDE was a two-arm randomized controlled trial. Intervention participants attended weekly group meetings for 6 months, then monthly group meetings for 6 months. Assessments were completed at baseline and at 6, 12, and 24 months. At 24 months, intervention participants lost 3.7% of baseline weight and control participants 2.1%, a non-significant difference. Fasting glucose results followed a similar pattern. There was a statistically significant difference, however, for fasting insulin-the intervention group's levels decreased between the end of the intensive intervention (at 6 months) and 24 months (10.1-7.91 μU/mL); control participants' levels increased (11.66 to 12.92 μU/mL) during this period. There were also fewer medical hospitalizations among intervention participants (5.7%) than controls (21.1%; χ(2) = 8.47, P = 0.004) during the 12- to 24-month post-intervention maintenance period. Weight change differences between arms diminished followi...Continue Reading

References

Oct 3, 1999·Annals of Internal Medicine·N C NetzerK P Strohl
Feb 24, 2001·Journal of Health Services Research & Policy·R Meenan
Jul 14, 2001·The American Journal of Clinical Nutrition·E ObarzanekUNKNOWN DASH Research Group
May 3, 2002·Journal of Neurology·Crispin JenkinsonUNKNOWN ALS-HPS Steering Group. Amyotrophic Lateral Sclerosis Health Profile Study
Feb 4, 2003·The American Journal of Psychiatry·Martina C M RyanJogin H Thakore
Jan 30, 2004·Diabetes Care·Jamy D ArdUNKNOWN PREMIER study
May 28, 2004·The Journal of Clinical Psychiatry·Susan L McElroyCharles B Nemeroff
Aug 4, 2005·Annals of Clinical Psychiatry : Official Journal of the American Academy of Clinical Psychiatrists·Roger S McIntyreSidney H Kennedy
Nov 2, 2005·Journal of Health and Social Behavior·Deborah Carr, Michael A Friedman
Jun 6, 2006·The Journal of Behavioral Health Services & Research·Susan V EisenThomas Idiculla
Jun 29, 2006·Health Promotion Practice·Kristine L FunkLawrence J Appel
May 30, 2007·Archives of Internal Medicine·Peter W F WilsonRalph B D'Agostino
Mar 13, 2008·JAMA : the Journal of the American Medical Association·Laura P SvetkeyUNKNOWN Weight Loss Maintenance Collaborative Research Group
Aug 22, 2009·Obesity·Pedro J TeixeiraLuís B Sardinha
Mar 30, 2010·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·J C M BarteW J E Bemelmans
Nov 26, 2010·The New England Journal of Medicine·Thomas Meinert LarsenUNKNOWN Diet, Obesity, and Genes (Diogenes) Project
Nov 22, 2011·The Psychiatric Clinics of North America·Meghan L ButrynThomas A Wadden
Jan 4, 2012·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·K M Ross MiddletonM G Perri
Mar 23, 2013·The New England Journal of Medicine·Gail L DaumitLawrence J Appel
May 17, 2013·Psychiatric Services : a Journal of the American Psychiatric Association·Stephen J BartelsKim T Mueser
Jan 5, 2014·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Stephanie RamageLinda McCargar
Apr 12, 2014·Journal of Behavioral Medicine·Phillip J BrantleyVictor J Stevens
Sep 16, 2014·The American Journal of Psychiatry·Carla A GreenVictor J Stevens
Nov 21, 2014·Nature·Mark Yarborough

❮ Previous
Next ❯

Citations

Jun 15, 2016·Sports Medicine·Davy VancampfortBrendon Stubbs
Jul 26, 2019·JBI Database of Systematic Reviews and Implementation Reports·Doreen MucheruLesley MacDonald-Wicks
Sep 9, 2019·Health Promotion Journal of Australia : Official Journal of Australian Association of Health Promotion Professionals·Doreen MucheruLesley MacDonald-Wicks
Jul 1, 2017·Journal of Endocrinological Investigation·A A Verhaegen, L F Van Gaal

❮ Previous
Next ❯

Clinical Trials Mentioned

NCT00790517

Software Mentioned

STRIDE
PREMIER
In

Related Concepts

Related Feeds

Antipsychotic Drugs

Antipsychotic drugs are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. Discover the latest research on antipsychotic drugs here

Antipsychotic-Induced Weight Gain

Antipsychotic-induced weight gain (aiwg) is a common adverse effect of this treatment, particularly with second-generation antipsychotics, and it is a major health problem around the world. Here are the latest discoveries pertaining to AIWG.