Welding fumes composition and their effects on blood heavy metals in albino rats

Toxicology Reports
I L Abdullahi, A Sani

Abstract

Toxic substances produced during welding include heavy metals, carbon monoxide, carbon dioxide, and nitrogen oxides. The study aims to evaluate the heavy metals concentration in welding fumes and the blood of the animals exposed to welding fumes. The fumes were collected from a welding site by a skilled welder and part of it was subjected to metals analysis. A total of 130 rats were divided into 13 groups. 12 groups were given doses calculated to correspond to real-life workers exposure regimes and 1 group served as control. The dosages were administered intratracheally after anesthetization weekly for 12 weeks. The animals were sacrificed and whole blood samples were collected for atomic absorption spectrophotometry. The metals in fumes analyzed were decreasing in order of Fe > K > Pb > Co > Cd > Ca > Ni > Mn > Zn > Cr > Al > Cu > Mg. Changes were observed in the behaviour of the test animals compared to the control indicating probable toxicity. The values of Pb, Cr, Fe, Mn, and Ni in the exposed animal's blood were higher than the control and increased relatively across the treatment groups. However, the values of Al and Zn were not significantly different from the control. These indicate that exposure to welding fumes having...Continue Reading

References

Jul 1, 1992·Environmental Health Perspectives·P Camner, A Johansson
Feb 1, 1992·American Journal of Respiratory Cell and Molecular Biology·K C StoneJ D Crapo
Feb 1, 1995·Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology·R F HendersonE B Barr
Dec 1, 1994·The Science of the Total Environment·M WolfspergerC Schlagenhaufen
Jun 1, 1995·Human & Experimental Toxicology·N HasanS Dodd
Dec 2, 1999·Journal of Toxicology and Environmental Health. Part a·J M AntoniniJ D Brain
May 2, 2000·Toxicological Sciences : an Official Journal of the Society of Toxicology·K E DriscollR B Schlesinger
Feb 24, 2001·Journal of Toxicology and Environmental Health. Part a·M J Reasor, J M Antonini
Nov 20, 2001·Scandinavian Journal of Work, Environment & Health·E Wergeland, B G Iversen
Jul 2, 2003·Toxicological Sciences : an Official Journal of the Society of Toxicology·Michael D TaylorJames M Antonini
Jul 10, 2003·Reproductive Toxicology·K DanadeviParamjit Grover
Dec 19, 2003·Journal of Toxicology and Environmental Health. Part a·Terry Gordon
Dec 19, 2003·Journal of Toxicology and Environmental Health. Part a·James M AntoniniJenny R Roberts
Feb 23, 2005·Occupational and Environmental Medicine·J Y KimD C Christiani
Jun 28, 2005·Forensic Science International : Synergy·Jean-Pierre GoulléChristian Lacroix
Mar 15, 2006·Journal of Occupational and Environmental Hygiene·James M AntoniniDavid G Frazer
Oct 31, 2008·Talanta·Ching-Jyi HorngCherng-Chyi Tzeng
Feb 13, 2009·Journal of Environmental Monitoring : JEM·Michael KeaneJames Antonini
Apr 16, 2011·Journal of Environmental Monitoring : JEM·Michael KeaneBean Chen
Feb 22, 2012·International Journal of Hygiene and Environmental Health·Jong Wha LeeJin Heon Lee
Jun 28, 2012·Journal of Immunotoxicology·Patti C Zeidler-ErdelyJames M Antonini
May 3, 2014·Journal of Toxicology and Environmental Health. Part a·Risto PopstojanovHong Kan
Jun 3, 2014·Particle and Fibre Toxicology·Pascal AndujarSophie Lanone
Jan 2, 2015·Toxicology Reports·Paula KauppiTimo Hannu

❮ Previous
Next ❯

Methods Mentioned

BETA
scanning electron microscopy
Atomic Absorption Spectrometry

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Bulletin of the Academy of Medicine, Toronto
F D CRUICKSHANK
Journal of Toxicology and Environmental Health. Part a
James M AntoniniJenny R Roberts
The New Zealand Medical Journal
C K Chew
The Annals of Occupational Hygiene
J Steel, J T Sanderson
© 2021 Meta ULC. All rights reserved