Well-differentiated thyroid carcinoma

American Journal of Otolaryngology
K SegalR Feinmesser

Abstract

This study presents our experience with 728 patients treated in our department for well-differentiated thyroid carcinoma between 1954-1994. The retrospective evaluation of the prognostic implications of the clinical and pathological findings was performed. Age, sex, histological variants, tumor size, and locoregional and distant spread were evaluated as risk factors in relation to the prognosis. During follow-up, which ranged from 1 to 31 years, 125 locoregional and/or distant metastases developed (17.2% of the patients), 87 of which occurred in the first 10 years after initial therapy. Thirty-two patients with papillary cancer and 20 with follicular cancer died of causes related to malignancy of the thyroid. The experience gained in our department has led us to adopt an aggressive approach in the treatment of patients with well-differentiated carcinoma of the thyroid gland.

References

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Citations

May 2, 2006·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Karl SegalAron Popovtzer
Oct 3, 2006·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Aron PopovtzerKarol Segal
Oct 18, 2006·Thyroid : Official Journal of the American Thyroid Association·Alexandra LubinaAvraham Karasik
Nov 2, 2014·Seminars in Nuclear Medicine·Valeria M MoncayoNaomi P Alazraki
Mar 1, 2012·Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición·Cintia González BlancoAlberto de Leiva Hidalgo
Apr 4, 2000·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·D FlanaganM Armitage
Feb 24, 2001·Clinical Oncology : a Journal of the Royal College of Radiologists·UNKNOWN Regional Thyroid Cancer Group
Sep 25, 2001·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·F O BlackS C Pesznecker
Oct 30, 1999·Clinical Otolaryngology and Allied Sciences·R M WalshJ Franklyn
Aug 22, 2007·Journal of Surgical Oncology·Mehmet Ali GulcelikHaluk Alagol
Feb 24, 2010·Journal of the Association for Research in Otolaryngology : JARO·Gene Y FridmanCharles C Della Santina
Mar 4, 2000·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·N S GoldsteinJ S Neill
Oct 20, 2006·Acta Oto-laryngologica·Anna HafstromMans Magnusson
Nov 30, 2010·Experimental Brain Research·Matthew R SchererMichael C Schubert
Jan 29, 2013·Journal of the Association for Research in Otolaryngology : JARO·Natan S DavidovicsCharles C Della Santina
Sep 10, 2013·Journal of the Association for Research in Otolaryngology : JARO·Chenkai DaiCharles C Della Santina

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