Wells' syndrome, or eosinophilic cellulitis, is characterized clinically by an acute dermatitis resembling cellulitis, which evolves into violaceous plaques that resolve spontaneously without scarring. The histopathologic features are dynamic, starting with dermal edema and infiltration of eosinophils, the development of "flame figures," and finishing with the appearance of phagocytic histiocytes. We present the clinical and histopathologic features of seven cases of eosinophilic cellulitis.
Eosinophilic cellulitis (Wells' syndrome): ultrastructural study of a case with circulating immune complexes
Eosinophilic infiltration with flame figures. A distinctive tissue reaction seen in Wells' syndrome and other diseases
Immunofluorescence identification of eosinophil granule major basic protein in the flame figures of Wells' syndrome
Eosinophilic cellulitis (Wells' syndrome): histologic and clinical features in arthropod bite reactions
Eosinophilic annular erythema: an expression of the clinical and pathological polymorphism of Wells syndrome
Urticarial lesions: if not urticaria, what else? The differential diagnosis of urticaria: part I. Cutaneous diseases
Comparison of clinical history and dermatologic findings in 29 dogs with severe eosinophilic dermatitis: a retrospective analysis
Bullous eosinophilic cellulitis succession with eosinophilic pustular folliculitis without eosinophilia
Pruritic nodules and plaques on the arms with blisters in a patient with chronic lymphocytic leukemia
Feline eosinophilic dermatoses: a retrospective immunohistochemical and ultrastructural study of extracellular matrix remodelling
Persistent urticaria characterized by recurrent lasting urticarial erythema with histological features of prominent perivascular eosinophilic infiltration
Diagnosis and management of eosinophilic cellulitis (Wells' syndrome): A case series and literature review
Wells syndrome and chronic spontaneous urticaria: report of four cases successfully treated with omalizumab
Luna stain: a simple and cost-effective diagnostic tool helps in detecting eosinophilic granules deposition of flame figures and aids in diagnosing eosinophilic cellulitis "Wells Syndrome"
Cellulitis (erysipelas) is a recurring and debilitating bacterial infection of the skin and underlying tissue. Discover the latest research on cellulitis here.