PMID: 9417174Jan 7, 1998Paper

Wernicke encephalopathy and beriberi during total parenteral nutrition attributable to multivitamin infusion shortage

Pediatrics
J S HahnD Bass

Abstract

Wernicke encephalopathy (WE) is an acute neurologic disorder characterized by a triad of ophthalmoplegia, ataxia, and mental confusion. WE is attributable to thiamine (vitamin B1) deficiency. Beriberi is the systemic counterpart of thiamine deficiency and often manifests in cardiovascular collapse. WE is usually associated with alcoholism and malnutrition. It has also been seen in people with gastrointestinal diseases with malabsorption. Patients who have received total parenteral nutrition (TPN) without proper replacement of thiamine have also developed WE. Since November 1996, there has been a shortage of multivitamin infusion (MVI). Many patients who were on chronic TPN with MVI ceased to receive the MVI and were converted to an oral form of the multivitamin. As a result, there have been several reports of children and adults on TPN who have developed WE as a result of thiamine deficiency. With this case report, we bring to attention the association of the MVI shortage and WE. Early diagnosis of WE is important, because if it is treated with thiamine in the acute stages, the neurologic and cardiovascular abnormalities can be reversed. We report a 20-year-old female patient with Crohn's disease who developed WE as a result of...Continue Reading

Citations

Feb 4, 2010·World Journal of Pediatrics : WJP·Jose GreensponSamuel M Alaish
Jul 25, 2000·Journal of Chromatography. a·P L Lynch, I S Young
May 18, 1999·Pediatric Neurology·M M VasconcelosC R Berditchevsky
Feb 2, 2006·Journal of Clinical and Experimental Neuropsychology·Anne B SerenoSusan V Szapiel
Feb 16, 2006·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Salvador ResinoUNKNOWN Spanish Group of Paediatric HIV Infection
Feb 6, 2013·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Antonio Costantini, Maria Immacolata Pala
Sep 26, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ross PerkoKaren D Wright
Feb 12, 2014·The American Journal of Case Reports·Ling LongZheng-Qi Lu
Dec 19, 2012·Journal of Pediatric Neurosciences·Riaz Ahmed
Aug 28, 2014·Pediatric Neurology·Aviva Mimouni-BlochAviva Fattal-Valevski
Feb 2, 2006·Obstetrics and Gynecology·Tamila SelitskyHenry J Schiavello
Aug 22, 2013·Current Psychiatry Reports·Brenda Bursch, Marcy Forgey
Oct 7, 2006·Current Opinion in Gastroenterology·P Kitchen, A Forbes
Jan 18, 2013·Digestive Diseases·Stephan R Vavricka, Gerhard Rogler
Jan 20, 2011·The International Journal of Neuroscience·A RufaA Federico
Nov 20, 2012·Psychosomatics·Elie Isenberg-GrzedaStephen E Nicolson
Nov 26, 2009·Pediatric Clinics of North America·David L Suskind
Nov 26, 2009·Pediatric Clinics of North America·Charmaine H Mziray-Andrew, Timothy A Sentongo
Oct 22, 2008·Nutrition·Francesco Francini-PesentiLorenza Caregaro
Nov 23, 2012·International Journal of Dermatology·Lara Wine Lee, Albert C Yan
Aug 4, 2004·The Journal of Pediatrics·Alexander TowbinStephen R Daniels
Nov 22, 2015·Digestive Diseases and Sciences·Danielle Barnes, John Kerner
Mar 10, 2015·La Presse médicale·Tarik AdiouiAziz Aourarh
Dec 18, 2014·World Journal of Pediatrics : WJP·Matt Lallas, Jay Desai
Jun 2, 2017·Annals of the American Thoracic Society·Harin PatelCarey C Thomson
Aug 7, 2014·JPEN. Journal of Parenteral and Enteral Nutrition·Yong Sing Da SilvaCameron Dezfulian
Dec 18, 2014·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Marilù GiacaloneFrancesco Forfori
Jun 26, 2012·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Vincent W VanekUNKNOWN American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) Board of Directors
Nov 23, 2006·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·M Patricia Fuhrman
Apr 4, 2017·The Journal of International Medical Research·Hudong LiangTao Jin
Feb 28, 2019·JPEN. Journal of Parenteral and Enteral Nutrition·Renée BlaauwMette M Berger
Dec 15, 2019·Muscle & Nerve·Kelly G Gwathmey, James Grogan
Dec 11, 2019·Journal of Pediatric Gastroenterology and Nutrition·Susan Hill
Apr 24, 2015·Expert Review of Gastroenterology & Hepatology·Bincy P Abraham
Mar 14, 2017·Clinical Practice and Cases in Emergency Medicine·Darshan Thota, Sherri Rudinsky
Feb 4, 2003·Alimentary Pharmacology & Therapeutics·J Goh, C A O'Morain
May 28, 2019·Pediatric Dermatology·Lauren E WizniaVikash Oza
Jan 25, 2020·Journal of Pediatric Gastroenterology and Nutrition·Susan Hill
Feb 22, 2021·Nutrition·Erik OudmanAlbert Postma

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.