Abstract
West Nile virus (WNV) is the most commonly reported mosquito-borne disease in the USA. California reports more WNV disease than any other state. We identified WNV-associated hospitalizations from 2004 through 2017 in California and estimated hospitalization incidence using Patient Discharge Data. We described demographic, geographic, and clinical characteristics of WNV hospitalizations; identified risk factors for in-hospital death; and tabulated hospitalization charges. From 2004 through 2017, 3109 Californians were hospitalized with WNV (median, 214 patients/year; range, 72-449). The majority were male (1983; 63.8%) and aged ≥60 years (1766; 56.8%). The highest median annual hospitalization rate (0.88 hospitalizations/100 000 persons) was in the Central Valley, followed by southern California (0.59 hospitalizations/100 000 persons). Most patients (2469; 79.4%) had ≥1 underlying condition, including hypertension, cardiovascular disease, diabetes, chronic kidney disease, or immunosuppression due to medications or disease. Median hospitalization length of stay was 12 days (interquartile range, 6-23 days). During hospitalization, 1317 (42%) patients had acute respiratory failure and/or sepsis/septic shock, 772 (24.8%) experienced...Continue Reading
References
Oct 1, 1975·The Journal of the American Dental Association·J B Murray
Aug 11, 2001·Lancet·F MostashariG L Campbell
Sep 7, 2002·The Lancet Infectious Diseases·Grant L CampbellDuane J Gubler
Apr 19, 2003·BMJ : British Medical Journal·Tom SolomonMacpherson Mallewa
Mar 17, 2004·Vector Borne and Zoonotic Diseases·Daniel R O'LearyGrant L Campbell
Oct 27, 2004·Emerging Infectious Diseases·Armineh ZohrabianLyle R Petersen
Jul 19, 2005·Emerging Infectious Diseases·James J SejvarLyle R Petersen
May 5, 2006·Epidemiology and Infection·K MurrayR B Tesh
Aug 10, 2006·Intensive Care Medicine·Fekri AbrougFadhel Najjar
Aug 15, 2006·Reviews in Medical Virology·James J Sejvar, Anthony A Marfin
May 23, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·James J Sejvar
May 1, 1942·American Journal of Public Health and the Nation's Health·B F Howitt
Apr 29, 2008·Emerging Infectious Diseases·Ryan M CarneyVicki Kramer
Mar 6, 2010·Emerging Infectious Diseases·Loren M BarberRobert K D Peterson
Jul 6, 2012·The American Journal of Tropical Medicine and Hygiene·Nicole P LindseyMarc Fischer
Jul 19, 2013·JAMA : the Journal of the American Medical Association·Lyle R PetersenRoger S Nasci
Feb 11, 2014·Viruses·James J Sejvar
Feb 12, 2014·The American Journal of Tropical Medicine and Hygiene·J Erin StaplesMarc Fischer
Apr 20, 2014·PLoS Pathogens·Amelia K PintoMichael S Diamond
Aug 13, 2014·Pediatrics·James T GaensbauerMarc Fischer
Jul 15, 2015·The Lancet Infectious Diseases·Hetal PatelMark P Nelder
Jan 20, 2017·MMWR. Morbidity and Mortality Weekly Report·Elisabeth Krow-LucalJ Erin Staples
Sep 8, 2017·BMC Infectious Diseases·Man Wah YeungBeate Sander
Jan 11, 2018·Diseases·Mohan RudrappaOleg Chernyshev
Jan 13, 2018·MMWR. Morbidity and Mortality Weekly Report·Alexis BurakoffNicole P Lindsey
Jul 11, 2018·PloS One·Alaa BadawiPaul Arora
Oct 16, 2018·Frontiers in Immunology·Gu-Lung LinAndrew J Pollard
Sep 21, 2019·Emerging Infectious Diseases·Najwa OuhoummaneFrançois Milord