West Nile virus infection among pregnant women in a northern Colorado community, 2003 to 2004

Pediatrics
Jan E PaisleyEdward B Hayes

Abstract

Since West Nile virus (WNV) was first detected in New York in 1999, it has spread across North America and become a major public health concern. In 2002, the first documented case of intrauterine WNV infection was reported, involving an infant with severe brain abnormalities. To determine the frequencies of WNV infections during pregnancy and of intrauterine WNV infections, we measured WNV-specific antibodies in cord blood from infant deliveries after a community-wide epidemic of WNV disease. Five hundred sixty-six pregnant women who presented to Poudre Valley Hospital (Fort Collins, CO) for delivery between September 2003 and May 2004 provided demographic and health history data through self-administered questionnaires and hospital admission records. Umbilical cord blood was collected from 549 infants and screened for WNV-specific IgM and IgG antibodies with enzyme-linked immunosorbent assays, with confirmation by plaque-reduction neutralization tests. Newborn growth parameters, Apgar scores, and hearing test results were recorded. Four percent (95% confidence interval: 2.4-5.7%) of cord blood samples tested positive for WNV-specific IgG antibodies. No cord blood samples were positive for WNV-specific IgM antibodies. There wer...Continue Reading

References

Mar 4, 1998·Tropical Medicine & International Health : TM & IH·S de A NishiokaH L Costa
Feb 13, 1999·Vaccine·E RobertM Reuvers
Dec 10, 1999·The Journal of Pediatrics·A NaessensW Foulon
Jul 14, 2000·Journal of Tropical Pediatrics·A K DeorariM Singh
May 3, 2002·Clinical and Diagnostic Laboratory Immunology·Denise A MartinJohn T Roehrig
Oct 1, 2003·American Journal of Ophthalmology·Samuel G AlpertLéon Paul Noël
Jan 1, 2004·The Pediatric Infectious Disease Journal·Tara L Greenhow, Peggy Sue Weintrub
May 4, 2004·Pediatrics·Edward B Hayes, Daniel R O'Leary

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Citations

Oct 31, 2006·The Pediatric Infectious Disease Journal·Edward B Hayes
Mar 28, 2013·Case Reports in Infectious Diseases·Robert D StewartJeanne S Sheffield
Sep 2, 2015·Expert Review of Anti-infective Therapy·Luisa BarzonGiorgio Palù
Jan 18, 2016·Microbes and Infection·Jason A Tetro
Jul 15, 2015·The Lancet Infectious Diseases·Hetal PatelMark P Nelder
Jun 23, 2009·Journal of Travel Medicine·Gerd D BurchardJane Zuckerman
May 26, 2016·Birth Defects Research. Part A, Clinical and Molecular Teratology·Gabriella PridjianDawn M Wesson
Apr 12, 2012·World Journal of Virology·Miguel A Martín-Acebes, Juan-Carlos Saiz
Jun 9, 2018·Paediatric and Perinatal Epidemiology·Taylor Z MannCarrie K Shapiro-Mendoza
Mar 11, 2016·Journal of Virology·Helen M Lazear, Michael S Diamond
May 5, 2009·Paediatrics & Child Health
Mar 5, 2020·Molecular Biology Reports·Francesca RombiSharon Yeoh
Jun 10, 2016·Clinical Microbiology Reviews·Alice PanchaudDavid Baud

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